Jurisic M, Andric M, dos Santos J N, Jurisic V
University of Belgrade, School of Dentistry, Belgrade, Serbia.
J BUON. 2012 Apr-Jun;17(2):237-44.
Keratocystic odontogenic tumors (KCOTs) are benign but locally aggressive lesions of the gnathic skeleton with high propensity to recur following surgical treatment. High proliferative activity of KCOTs epithelial cells is considered as one of the factors contributing to their aggressive clinical behavior. Aggressive growth within the jaws, tendency to invade surrounding anatomical structures and occasional malignant alteration are the features that distinguish KCOTs from other types of odontogenic tumors. Due to their unique clinical and biological features, KCOTs still present an important problem in oral and maxillofacial surgery. This is especially true when a choice of the most appropriate treatment modality should be made. Establishing balance between effective reduction of recurrence risk and selection of a less aggressive surgical procedure is an issue that should be carefully considered for each individual patient.
牙源性角化囊性瘤（KCOTs）是颌骨的良性但具有局部侵袭性的病变，手术治疗后复发倾向高。KCOTs上皮细胞的高增殖活性被认为是导致其侵袭性临床行为的因素之一。在颌骨内的侵袭性生长、侵犯周围解剖结构的倾向以及偶尔的恶性转变是将KCOTs与其他类型牙源性肿瘤区分开来的特征。由于其独特的临床和生物学特征，KCOTs在口腔颌面外科中仍然是一个重要问题。当需要选择最合适的治疗方式时尤其如此。在有效降低复发风险和选择侵袭性较小的手术程序之间建立平衡是一个应针对每个患者仔细考虑的问题。
