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牙源性角化囊性瘤:对来自都灵大学的261例病变的流行病学、临床和放射学特征进行初步回顾性研究

Keratocystic odontogenic tumor (odontogenic keratocyst): preliminary retrospective review of epidemiologic, clinical, and radiologic features of 261 lesions from University of Turin.

作者信息

Boffano Paolo, Ruga Emanuele, Gallesio Cesare

机构信息

Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy.

出版信息

J Oral Maxillofac Surg. 2010 Dec;68(12):2994-9. doi: 10.1016/j.joms.2010.05.068. Epub 2010 Oct 23.

Abstract

PURPOSE

To analyze and discuss the demographic, clinical, and surgical aspects of 261 surgically treated keratocystic odontogenic tumors.

PATIENTS AND METHODS

A retrospective review was performed of all cases of treated keratocystic odontogenic tumors. Statistical analysis was used to search for associations among age, presenting symptoms, location, dimension, and locularity.

RESULTS

Keratocystic odontogenic tumors most commonly occurred in patients in the third and fourth decades of life. The ratio of males to females was 2:1. The mandibular angle region was the most frequently involved site. Significant associations were found between multilocular lesions and lesions larger than 31 mm (P < .00000005), a mandibular site and larger lesions (P < .05), patients younger than 41 years old and multilocular lesions (P < .05), and younger patients and larger lesions (P < .00005).

CONCLUSION

It is likely that most multilocular, larger (and probably aggressive) lesions are found in patients younger than 41 years of age.

摘要

目的

分析并讨论261例接受手术治疗的牙源性角化囊性瘤的人口统计学、临床及外科手术方面的情况。

患者与方法

对所有接受治疗的牙源性角化囊性瘤病例进行回顾性研究。采用统计学分析来探寻年龄、临床表现、部位、大小及分房情况之间的关联。

结果

牙源性角化囊性瘤最常见于30至40岁的患者。男女比例为2:1。下颌角区域是最常受累部位。发现多房性病变与大于31毫米的病变之间存在显著关联(P <.00000005),下颌部位与较大病变之间存在显著关联(P <.05),41岁以下患者与多房性病变之间存在显著关联(P <.05),以及年轻患者与较大病变之间存在显著关联(P <.00005)。

结论

很可能大多数多房性、较大(且可能具有侵袭性)的病变见于41岁以下的患者。

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