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In vivo spin-trapping of trichloromethyl radicals formed from CCl4.

作者信息

Lai E K, McCay P B, Noguchi T, Fong K L

出版信息

Biochem Pharmacol. 1979 Jul 15;28(14):2231-5. doi: 10.1016/0006-2952(79)90212-0.

DOI:10.1016/0006-2952(79)90212-0
PMID:227403
Abstract
摘要

相似文献

1
In vivo spin-trapping of trichloromethyl radicals formed from CCl4.四氯化碳生成的三氯甲基自由基的体内自旋捕获
Biochem Pharmacol. 1979 Jul 15;28(14):2231-5. doi: 10.1016/0006-2952(79)90212-0.
2
Electron spin resonance study of homolytic cleavage of carbon tetrachloride in rat liver: trichloromethyl free radicals.大鼠肝脏中四氯化碳均裂裂解的电子自旋共振研究:三氯甲基自由基
Pharmacol Res Commun. 1976 Aug;8(4):429-34. doi: 10.1016/0031-6989(76)90042-4.
3
Spin trapping of free radical metabolites of carbon tetrachloride in vitro and in vivo: effect of acute ethanol administration.四氯化碳自由基代谢产物在体外和体内的自旋捕获:急性乙醇给药的影响
Toxicol Appl Pharmacol. 1992 Jan;112(1):17-23. doi: 10.1016/0041-008x(92)90274-v.
4
Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat.对四氯化碳在大鼠肝微粒体组分、分离的肝细胞以及大鼠体内经代谢活化形成的自由基产物的自旋捕集研究。
Biochem J. 1982 May 15;204(2):593-603. doi: 10.1042/bj2040593.
5
Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.四氯化碳代谢过程中氧中心和碳中心自由基的形成。体内和体外脂质自由基的观察。
J Biol Chem. 1984 Feb 25;259(4):2135-43.
6
Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism in vitro and in vivo.通过自旋捕集法检测到的三氯甲基自由基自旋加合物在四氯化碳体外和体内代谢过程中归属的确证。
Biochem Biophys Res Commun. 1980 Jun 30;94(4):1154-60. doi: 10.1016/0006-291x(80)90540-9.
7
Reduction of CCl4 to the trichloromethyl radical by lignin peroxidase H2 from Phanerochaete chrysosporium.来自黄孢原毛平革菌的木质素过氧化物酶H2将四氯化碳还原为三氯甲基自由基。
Biochem Biophys Res Commun. 1993 Mar 31;191(3):887-92. doi: 10.1006/bbrc.1993.1300.
8
Study of reproducibility of spin trapping results in the use of C-phenyl-N-tert-butyl nitrone (PBN) for trichloromethyl radical detection in CCl4 metabolism by rat liver microsomal dispersions. Biological spin trapping I.使用C-苯基-N-叔丁基硝酮(PBN)检测大鼠肝微粒体分散液中四氯化碳代谢产生的三氯甲基自由基时自旋捕获结果的重现性研究。生物自旋捕获I。
J Biochem Biophys Methods. 1994 Dec;29(3-4):189-205. doi: 10.1016/0165-022x(94)90032-9.
9
An update on antioxidant theory: spin trapping of trichloromethyl radicals in vivo.抗氧化理论的更新:体内三氯甲基自由基的自旋捕获
Ann N Y Acad Sci. 1982;393:23-31. doi: 10.1111/j.1749-6632.1982.tb31229.x.
10
In vivo radical trapping and biliary secretion of radical adducts of carbon tetrachloride-derived free radical metabolites.四氯化碳衍生的自由基代谢产物的自由基捕获及胆汁分泌的体内研究
Drug Metab Dispos. 1988 Nov-Dec;16(6):813-7.

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Tandem mass spectrometry study of C-phenyl-N-tert-butyl nitrone spin adducts from in vitro rat liver microsomal metabolism of bromotrichloromethane and carbon tetrachloride.串联质谱法研究溴三氯甲烷和四氯化碳在体外大鼠肝微粒体代谢中的 C-苯-N-叔丁基硝酮自旋加合物。
J Am Soc Mass Spectrom. 1995 Sep;6(9):847-53. doi: 10.1016/1044-0305(95)00328-B.
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Spin trapping of hydroperoxyl radical by a cyclic nitrone conjugated to -cyclodextrin: a computational study.
与β-环糊精共轭的环状硝酮对氢过氧自由基的自旋捕获:一项计算研究。
Theor Chem Acc. 2012 Jul 1;131. doi: 10.1007/s00214-012-1248-1.
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Electron spin resonance. Part one: a diagnostic method in the biomedical sciences.电子自旋共振。第一部分:生物医学科学中的一种诊断方法。
Sci Prog. 2011;94(Pt 1):16-96. doi: 10.3184/003685011X12982218769939.
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Nitrones as therapeutics.硝酮作为治疗药物。
Free Radic Biol Med. 2008 Nov 15;45(10):1361-74. doi: 10.1016/j.freeradbiomed.2008.08.017. Epub 2008 Aug 29.
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Oxidative stress in silicosis: evidence for the enhanced clearance of free radicals from whole lungs.
Mol Cell Biochem. 1997 Mar;168(1-2):125-32. doi: 10.1023/a:1006850920080.
7
Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine.在磷脂囊泡中重组的人细胞色素P-450对四氯化碳的还原代谢:与二油酰磷脂酰胆碱结合的三氯甲基自由基的质谱鉴定
Proc Natl Acad Sci U S A. 1982 Apr;79(8):2678-82. doi: 10.1073/pnas.79.8.2678.
8
Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat.对四氯化碳在大鼠肝微粒体组分、分离的肝细胞以及大鼠体内经代谢活化形成的自由基产物的自旋捕集研究。
Biochem J. 1982 May 15;204(2):593-603. doi: 10.1042/bj2040593.
9
Detection of superoxide generated by endothelial cells.内皮细胞产生的超氧化物的检测。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7269-73. doi: 10.1073/pnas.81.23.7269.
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Free radicals and tissue injury: fact and fiction.自由基与组织损伤:事实与虚构
Br J Cancer Suppl. 1987 Jun;8:5-10.