Suppr超能文献

经耳前颞下窝入路切除腮腺区晚期恶性肿瘤

Preauricular infratemporal fossa approach for advanced malignant parotid tumors.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood, Illinois, USA.

出版信息

Laryngoscope. 2012 Sep;122(9):1949-53. doi: 10.1002/lary.23322. Epub 2012 Jun 27.

Abstract

OBJECTIVES/HYPOTHESIS: The aims of this study were to demonstrate the surgical technique involved in the preauricular infratemporal fossa (ITF) approach, outline the clinical indications for use of this technique, and present the results in using this approach in 159 patients with malignant parotid tumors. At the conclusion of this article, the reader should be able to understand the utility of the preauricular infratemporal fossa approach in the management of patients with advanced malignant parotid tumors.

STUDY DESIGN

This was a retrospective chart review of 159 patients treated at a tertiary care academic medical center following institutional review board approval.

METHODS

A comprehensive medical records review was performed for all patients with malignant parotid tumors who underwent a preauricular ITF approach between July 1988 and July 2010.

RESULTS

The most common presenting symptoms were pain and trismus, whereas the presence of a parotid mass and facial paralysis were the most common clinical signs. Mucoepidermoid and adenoid cystic carcinoma accounted for 63% of the tumors, and perineural invasion was found in nearly 71% of the patients. Despite negative surgical margins in 92% of the patients, local or regional tumor recurrence was found in 17% of the cases. The mean follow-up time was 12.8 years.

CONCLUSIONS

The preauricular ITF approach should be used in the surgical extirpation of advanced malignant parotid neoplasms. This technique provides proximal facial nerve identification, internal carotid artery protection, and negative tumor margins at the skull base.

摘要

目的/假设:本研究旨在演示耳前颞下窝(ITF)入路的手术技术,概述该技术的临床适应证,并介绍在 159 例恶性腮腺肿瘤患者中使用该入路的结果。阅读本文后,读者应能够理解耳前颞下窝入路在治疗晚期恶性腮腺肿瘤患者中的作用。

研究设计

这是一项回顾性病例研究,对在获得机构审查委员会批准后于一家三级护理学术医疗中心接受治疗的 159 例恶性腮腺肿瘤患者进行了分析。

方法

对所有接受耳前 ITF 入路治疗的恶性腮腺肿瘤患者进行了全面的病历回顾,时间范围为 1988 年 7 月至 2010 年 7 月。

结果

最常见的首发症状是疼痛和牙关紧闭,而腮腺肿块和面瘫是最常见的临床体征。黏液表皮样癌和腺样囊性癌占肿瘤的 63%,近 71%的患者存在神经周围侵犯。尽管 92%的患者切缘阴性,但仍有 17%的患者出现局部或区域性肿瘤复发。平均随访时间为 12.8 年。

结论

耳前 ITF 入路应用于外科切除晚期恶性腮腺肿瘤。该技术可提供面神经近端识别、颈内动脉保护和颅底肿瘤阴性切缘。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验