Dobson Ruth, Ramagopalan Sreeram, Giovannoni Gavin
Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University, UK.
Mult Scler. 2012 Nov;18(11):1522-8. doi: 10.1177/1352458512453362. Epub 2012 Jun 27.
People with multiple sclerosis (MS) have many reasons to have low bone mineral density and an increased fracture risk. Osteoporosis is a major cause of morbidity and mortality, and is more common in people with MS than the general population. A number of studies have examined the relationship between multiple sclerosis and reduced bone mineral density. In this topical review we seek to address the risk of low bone mineral density, osteoporosis and fractures associated with MS, and make practical suggestions as to how this pertinent issue may be approached in clinical practice.
患有多发性硬化症(MS)的人有许多理由出现低骨矿物质密度和骨折风险增加的情况。骨质疏松症是发病和死亡的主要原因,在多发性硬化症患者中比普通人群更常见。多项研究已经探讨了多发性硬化症与骨矿物质密度降低之间的关系。在这篇专题综述中,我们旨在探讨与多发性硬化症相关的低骨矿物质密度、骨质疏松症和骨折风险,并就如何在临床实践中处理这个相关问题提出切实可行的建议。