Gong Lin, Liu Hui, Yang Kai-Xuan, Peng Zhi-Lan
Department of Obstetrics and Gynecology, Sichuan University, Chengdu, China.
Breast Care (Basel). 2012 Apr;7(2):150-152. doi: 10.1159/000337773. Epub 2012 Apr 24.
Reproductive tract sarcomas metastasizing to the breast are uncommon. To our knowledge, metastasis of vaginal leiomyosarcoma to the breast has not been previously reported in the literature. CASE REPORT: We present the first report of a FIGO stage IV primary vaginal leiomyosarcoma with metastases to the lung and left breast. Treatment included neoadjuvant chemotherapy followed by surgery and postoperative chemotherapy. Lung metastasis disappeared but recurred 14 months later in conjunction with left breast metastasis which was resected. CONCLUSION: Primary vaginal sarcoma with lung and breast metastases is very rare in female genital malignancies. We present this case to alert gynecologists to the need for early diagnosis and aggressive management.
转移至乳腺的生殖道肉瘤并不常见。据我们所知，阴道平滑肌肉瘤转移至乳腺此前尚无文献报道。病例报告：我们报告首例国际妇产科联盟（FIGO）IV期原发性阴道平滑肌肉瘤伴肺及左乳腺转移。治疗包括新辅助化疗，随后手术及术后化疗。肺转移消失，但14个月后复发并伴有左乳腺转移，予以切除。结论：原发性阴道肉瘤伴肺及乳腺转移在女性生殖系统恶性肿瘤中非常罕见。我们报告此病例以提醒妇科医生需早期诊断并积极治疗。
