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阴道平滑肌肉瘤:病例报告及文献综述

Leiomyosarcoma of the vagina: case report and literature review.

作者信息

Ahram J, Lemus R, Schiavello H J

机构信息

Department of Obstetrics and Gynecology, Wyckoff Heights Medical Center, Brooklyn, New York, USA.

出版信息

Int J Gynecol Cancer. 2006 Mar-Apr;16(2):884-91. doi: 10.1111/j.1525-1438.2006.00487.x.

Abstract

Leiomyosarcoma of the vagina is quite rare. Extensive search of the literature discloses 137 case reports published over the past 40 years. Collectively, these reports give only cursory guidelines for diagnosis, management, and prognosis. We add another case to the sparse literature on leiomyosarcoma of the vagina. Treatment consisted of surgical excision. Tumor was found to extend to the margin of the excised specimen. The malignancy quickly recurred with lung metastases and the patient died. The very poor prognosis associated with this lesion emphasizes the critical need for early diagnosis and expeditious therapy. In the interest of improving salvage by prompt recognition and intervention, it is important for health-care professionals to be knowledgeable about and alert to this condition.

摘要

阴道平滑肌肉瘤相当罕见。广泛查阅文献发现,在过去40年里共发表了137例病例报告。总体而言,这些报告仅给出了关于诊断、治疗和预后的粗略指导原则。我们在关于阴道平滑肌肉瘤的稀少文献中又增加了一例病例。治疗方法为手术切除。发现肿瘤已延伸至切除标本的边缘。恶性肿瘤很快复发并伴有肺转移,患者死亡。与该病变相关的极差预后凸显了早期诊断和快速治疗的迫切需求。为了通过及时识别和干预提高挽救成功率,医护人员了解并警惕这种情况非常重要。

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