Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Am J Ther. 2013 Jan;20(1):67-72. doi: 10.1097/MJT.0b013e31824d61a4.
Acute pulmonary embolism (PE) is a relatively rare but potentially fatal complication during the perioperative period. Its diagnosis is particularly challenging in the anesthetized patient, yet early diagnosis and treatment are essential in preventing morbidity and mortality. Preventative measures including anticoagulant treatment are well-established modalities in the management of venous thromboses and PE in the nonsurgical patient. However, a patient undergoing surgery suffering a new PE presents a unique challenge. Conventional treatment is often not an option in the perioperative period, as surgical bleeding may be equally life threatening as a PE. Therefore, techniques that target the embolism directly and avoid systemic anticoagulation seem to promise safer and more efficient treatment of the patient with PE in the perioperative period. Fast detection, correct diagnosis, and appropriate treatment are all essential in improving the outcome of this severe complication.
急性肺栓塞(PE)是围手术期相对罕见但潜在致命的并发症。在麻醉患者中,其诊断极具挑战性,但早期诊断和治疗对于预防发病率和死亡率至关重要。预防措施包括抗凝治疗,在非手术患者的静脉血栓形成和 PE 管理中已得到充分证实。然而,正在接受手术的患者发生新的 PE 会带来独特的挑战。在围手术期,常规治疗通常不是一种选择,因为手术出血可能与 PE 同样危及生命。因此,针对栓塞物直接治疗且避免全身抗凝的技术似乎有望为围手术期的 PE 患者提供更安全、更有效的治疗。快速检测、正确诊断和适当的治疗对于改善这种严重并发症的结局都至关重要。