Balli F, Del Bianco F, Savoini A, Bertolani P
Istituto di Clinica Pediatrica, Università di Modena, Italia.
Pediatr Med Chir. 1990 May-Jun;12(3):223-8.
Cow's milk protein intolerance (CMPI) is recognised as an important cause of protean symptoms in infants. There are no tests with enough specificity and sensibility to set up a diagnostic assay. We carried out preliminary study on children suffering from CMPI with the following aims: a) to ascertain the importance of the variation in circulating antibodies to cow's milk proteins in CMPI, b) to establish a useful screening tool to diagnose CMPI. Seventy-four subjects (s.) were studied and divided into four diagnostic groups as follows: Six s. (3 M, 3 F) suffering from CMPI mean age 4.8 +/- 3.9 months, assuming a diet containing cow's milk: I group. Eleven s. (O M, 7 F) suffering from CMPI mean age 7.8 +/- 4.6 months, assuming a cow's milk free diet, for several months (mean 4.5 +/- 1.5): II group. Nine s. (5 M, 4 F) suffering from enteropathies not cow's milk correlated, mean age 18.5 +/- 10.6 months, assuming a diet containing cow's milk: III group. Fourty-eight healthy s. (24 M, 24 F), mean age 10.5 +/- 4.3 months, assuming a diet containing cow's milk.(ABSTRACT TRUNCATED AT 250 WORDS)
牛奶蛋白不耐受（CMPI）被认为是婴儿出现多种症状的重要原因。目前尚无具有足够特异性和敏感性的检测方法来建立诊断试验。我们对患有CMPI的儿童进行了初步研究，目的如下：a）确定循环中针对牛奶蛋白的抗体变化在CMPI中的重要性，b）建立一种有用的筛查工具来诊断CMPI。研究了74名受试者，并将其分为以下四个诊断组：六名患有CMPI的受试者（3名男性，3名女性），平均年龄4.8±3.9个月，采用含牛奶饮食：第一组。11名患有CMPI的受试者（0名男性，7名女性），平均年龄7.8±4.6个月，采用无牛奶饮食数月（平均4.5±1.5）：第二组。9名患有与牛奶无关的肠病的受试者（5名男性，4名女性），平均年龄18.5±10.6个月，采用含牛奶饮食：第三组。48名健康受试者（24名男性，24名女性），平均年龄10.5±4.3个月，采用含牛奶饮食。（摘要截断于250字）
