Division of Surgical Oncology, Department of Surgery, Sealy Center for Cancer Cell Biology, University of Texas Medical Branch, Galveston, TX, USA.
J Gastrointest Surg. 2012 Sep;16(9):1641-4. doi: 10.1007/s11605-012-1949-8. Epub 2012 Jun 29.
Cancer biomarkers may be used for prevention (identification of patients at high risk for cancer), estimating prognosis and/or repsonse to conventional chemotherapies, or guide the use of specific targeted therapies. This overview provides examples in each category for gastrointestinal cancers and reviews current concepts in personalized medicine.
癌症生物标志物可用于预防(识别癌症高危患者)、评估预后和/或对常规化疗的反应,或指导特定靶向治疗的使用。本篇综述为胃肠道癌症各分类提供了相关实例,并回顾了个性化医学的现有概念。