Salim Raed, Braverman Meirav, Teitler Nava, Berkovic Ilanit, Suliman Abeer, Shalev Eliezer
Department of Obstetrics and Gynecology , Emek Medical Center, Afula and Rappaport Faculty of Medicine, Technion, Haifa, Israel.
J Matern Fetal Neonatal Med. 2012 Dec;25(12):2708-12. doi: 10.3109/14767058.2012.705394. Epub 2012 Jul 20.
To identify risk factors for infection following cesarean delivery (CD) and to investigate the effect of intervention on modifiable risk factors (MRF).
A prospective, two-period cohort intervention study. All CD performed between September 2006 and August 2007 (era 1) and between July 2009 and June 2010 (era 2) were included. Infection control program was implemented before era 2 and included a refresher course in aseptic and scrub techniques to all surgical teams. Infectious morbidity was recognized up to 30 days from the operation. Risk factors were identified by multiple logistic regressions.
A total of 1616 women included and analyzed during both eras. Logistic regression revealed that residency (rural as compared to urban), obesity and urgency of the CD were significant risk factors for infection. Prior to intervention, senior obstetricians had a lower infection rate than senior gynecologists (p = 0.02). Within both groups, the incidence in era 2 decreased and was comparable (obstetricians: 5.7 vs. 1.6%; p = 0.005; gynecologists: 12.7 vs. 1.1%; p = 0.003). Among the group of scrub nurses who took part in less than 20 CD during era 1, the intervention reduced significantly the infection rate during era 2 (p = 0.0002).
Surgical team is a MRF for infection following CD. Intervention decreased this unintended clinical effect attributed to surgical teams.
确定剖宫产术后感染的危险因素,并研究干预措施对可改变危险因素(MRF)的影响。
一项前瞻性、两阶段队列干预研究。纳入2006年9月至2007年8月(第1阶段)以及2009年7月至2010年6月(第2阶段)期间进行的所有剖宫产手术。在第2阶段之前实施了感染控制计划,包括为所有手术团队提供无菌和刷手技术的进修课程。术后30天内确认感染发病率。通过多元逻辑回归确定危险因素。
两个阶段共纳入并分析了1616名女性。逻辑回归显示,居住地(农村与城市相比)、肥胖和剖宫产的紧急程度是感染的重要危险因素。干预前,高级产科医生的感染率低于高级妇科医生(p = 0.02)。在两组中,第2阶段的发病率均有所下降且具有可比性(产科医生:5.7%对1.6%;p = 0.005;妇科医生:12.7%对1.1%;p = 0.003)。在第1阶段参与剖宫产手术少于20例的刷手护士组中,干预措施在第2阶段显著降低了感染率(p = 0.0002)。
手术团队是剖宫产术后感染的一个可改变危险因素。干预减少了归因于手术团队的这种意外临床影响。