血浆钙和维生素D对骨胶原的影响。对赖氨酸羟基化和交联形成的作用。
Influence of plasma calcium and vitamin D on bone collagen. Effects on lysine hydroxylation and crosslink formation.
作者信息
Dickson I R, Eyre D R, Kodicek E
出版信息
Biochim Biophys Acta. 1979 Nov 15;588(1):169-73. doi: 10.1016/0304-4165(79)90381-7.
PMID:227472
Abstract
In chick bone collagen the degree of lysine hydroxylation and the magnitude of the crosslink ratio dihydroxylysinonorleucine/hydroxylysinonorleucine were both found to be inversely related to the concentration of plasma calcium. Lysine hydroxylation was also affected by a second factor related to vitamin D status.
摘要
在鸡骨胶原蛋白中，发现赖氨酸羟基化程度以及交联比二羟基赖氨酰正亮氨酸/羟基赖氨酰正亮氨酸的大小均与血浆钙浓度呈负相关。赖氨酸羟基化还受到与维生素D状态相关的第二个因素的影响。
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