维生素D缺乏时的骨胶原代谢
Bone collagen metabolism in vitamin D deficiency.
作者信息
Barnes M J, Constable B J, Morton L F, Kodicek E
出版信息
Biochem J. 1973 Jan;132(1):113-5. doi: 10.1042/bj1320113.
Abstract
Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized. However, the extent of lysine hydroxylation in both alpha1- and alpha2-chains is increased, by approx. 15-30% in the rat and by 50% in the chick.
摘要
放射性同位素研究表明，佝偻病大鼠和小鸡骨骼骨干中合成的胶原蛋白在链组成上与正常合成的胶原蛋白相似。然而，α1链和α2链中赖氨酸羟基化的程度都有所增加，在大鼠中约增加15%-30%，在小鸡中增加50%。
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THE FORMATION OF COLLAGEN HYDROXYLYSINE STUDIED WITH TRITIATED LYSINE.用氚标记赖氨酸研究胶原羟赖氨酸的形成
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Embryonic skin collagen. Replacement of the type of aldimine crosslinks during the early growth period.胚胎皮肤胶原蛋白。早期生长阶段醛亚胺交联类型的替代。
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Isolation and characterization of the peptides derived from the alpha-1 chain of chick bone collagen after cyanogen bromide cleavage.溴化氰裂解后鸡骨胶原α-1链衍生肽段的分离与表征
Biochemistry. 1969 Jan;8(1):30-9. doi: 10.1021/bi00829a006.
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