来自在乙二醇上生长的黄杆菌属的磷酸甘油酸变位酶的动力学控制
Kinetic control of phosphoglycerate mutase from Flavobacterium sp. grown on ethylene glycol.
作者信息
Willetts A
出版信息
Biochim Biophys Acta. 1979 Nov 15;588(1):20-5. doi: 10.1016/0304-4165(79)90366-0.
PMID:227474
Abstract
A species of Flavobacterium able to oxidise ethylene glycol to pyruvate via glyoxylate, glycerate, 2-phosphoglycerate and phosphoenolpyruvate exploits phosphoglycerate mutase to initiate gluconeogenesis. Partially purified phosphoglycerate mutase from this bacterium is independent of adenylate charge control but is activated by phosphoenolpyruvate. The possible significance of this regulation is discussed.
摘要
一种黄杆菌能够通过乙醛酸、甘油酸、2-磷酸甘油酸和磷酸烯醇丙酮酸将乙二醇氧化为丙酮酸，该菌利用磷酸甘油酸变位酶启动糖异生作用。从这种细菌中部分纯化得到的磷酸甘油酸变位酶不受腺苷酸电荷控制，但可被磷酸烯醇丙酮酸激活。文中讨论了这种调节作用可能具有的意义。
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