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原发性翼状胬肉羊膜移植与单纯巩膜术式的比较

Amniotic membrane transplantation in primary pterygium compared with bare sclera technique.

作者信息

Arain Muhammad Aamir, Yaqub Muhammad Amer, Ameen Sameer Shahid, Iqbal Zamir, Naqvi Abid Hussain, Niazi Muhammad Khizar

机构信息

Department of Ophthalmology, Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

出版信息

J Coll Physicians Surg Pak. 2012 Jul;22(7):440-3.

PMID:22747864
Abstract

OBJECTIVE

To compare the excision of primary pterygium by bare sclera technique and excision combined with amniotic membrane transplantation (AMT).

STUDY DESIGN

An experimental study.

PLACE AND DURATION OF STUDY

Eye Department, Military Hospital, Rawalpindi, presently known as Armed Forces Institute of Ophthalmology, Rawalpindi, from May 2007 to July 2008.

METHODOLOGY

A pilot study of 70 patients was conducted. Patients were divided in two groups. In group I, pterygium excision was done by bare sclera technique while in group II, AMT was done after excision. Patients were followed for 6 months. Proportion of recurrence of pterygium was noted in each group and compared with chi-square test with significance at p < 0.05.

RESULTS

Number of patients who presented with recurrence of pterygium in group-I were 12 (37.5%) and in group-II were 4 (12.9%). Chi-square tests showed that there was a statistically significant difference in frequency of recurrence between the two groups (p = 0.025).

CONCLUSION

AMT after excision of pterygium appeared to be safe and effective way of treating primary pterygium as compared to bare sclera technique due to lesser recurrence at 6 months.

摘要

目的

比较单纯巩膜切除术与联合羊膜移植术(AMT)切除原发性翼状胬肉的效果。

研究设计

一项实验研究。

研究地点及时间

2007年5月至2008年7月,位于拉瓦尔品第的军事医院眼科,现称为拉瓦尔品第武装部队眼科研究所。

方法

对70例患者进行了一项初步研究。患者分为两组。第一组采用单纯巩膜切除术切除翼状胬肉,第二组在切除术后进行羊膜移植术。对患者进行了6个月的随访。记录每组翼状胬肉复发的比例,并采用卡方检验进行比较,显著性水平为p < 0.05。

结果

第一组出现翼状胬肉复发的患者有12例(37.5%),第二组有4例(12.9%)。卡方检验显示,两组之间复发频率存在统计学显著差异(p = 0.025)。

结论

与单纯巩膜切除术相比,翼状胬肉切除术后进行羊膜移植术似乎是治疗原发性翼状胬肉的一种安全有效的方法,因为在6个月时复发率较低。

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Evaluation of the Efficacy of Different Pterygium Surgeries in Polish Caucasian Population.
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Clin Ophthalmol. 2018 Nov 19;12:2347-2362. doi: 10.2147/OPTH.S186543. eCollection 2018.
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