Uematsu T, Sato R
Department of Pharmacology, Hamamatsu University School of Medicine, Japan.
Ther Drug Monit. 1990 Nov;12(6):582-3. doi: 10.1097/00007691-199011000-00012.
The patients reported in our previous paper were followed further, by analyzing hair samples collected monthly for 4 or 5 months, while growing hair continues to reflect the individual dosage history of haloperidol. In patients in whom the drug had been discontinued, the portion of hair that reflected the change of dose continued to move upward. In hair of patients in whom the dosage was decreased by one-half, the portion of change was also shown to move upward. These results indicate the potential usefulness of hair for assessing the individual past dosage history of haloperidol.
我们在之前的论文中报告过的患者被进一步随访，通过分析连续4或5个月每月采集的毛发样本，因为生长中的毛发持续反映了个体的氟哌啶醇用药史。在已停药的患者中，反映剂量变化的毛发部分继续向上移动。在剂量减半的患者的毛发中，变化部分也显示向上移动。这些结果表明毛发在评估个体过去的氟哌啶醇用药史方面具有潜在的用途。
