Goncharuk V D
Tsitologiia. 1990;32(5):474-80.
Cell bodies of cardiovascular receptors localized in the ganglion nodosum of rabbits exposed to experimental emotional stress were studied with the light and electron microscope. Two groups of animals were selected for investigation. Under emotional stress rabbits of one group demonstrated almost unchanged arterial pressure and only a small increase in heart rate, while animals of the other group displayed strongly marked disturbances of their blood circulation leading to the lethal outcome at the end of experiment. In the first group rabbits, the microscopic anatomy and ultrastructure of the nodose ganglion neurons indicated an increased activity in the nerve cell. At the same time, morphological evidences of exhaustion were revealed in neurons of the nodose ganglion of the second group rabbits. A possible role of the distortion of the afferent information in pathogenesis of cardiovascular disorders under emotional stress is discussed.
运用光学显微镜和电子显微镜,对暴露于实验性情绪应激的家兔结节神经节中的心血管感受器的细胞体进行了研究。选取两组动物进行调查。在情绪应激状态下,一组家兔的动脉血压几乎未变,心率仅略有增加,而另一组家兔则表现出明显的血液循环紊乱,最终在实验结束时导致死亡。在第一组家兔中,结节神经节神经元的微观解剖结构和超微结构表明神经细胞的活性增加。与此同时,在第二组家兔的结节神经节神经元中发现了衰竭的形态学证据。讨论了情绪应激下传入信息失真在心血管疾病发病机制中的可能作用。