Mikunis R I, Demidiuk V T
Vrach Delo. 1990 Apr(4):68-9.
Noninvasive methods (kinetocardiography, pneumotachometry, sphygmomanometry) were used in 32 patients chronic obstructive pulmonary diseases (chronic obstructive bronchitis, bronchial asthma) to study the effect of foridon (calcium antagonist) on the bronchial patency, lesser and greater circulation arterial pressure during single intakes and course treatment. Single intake had no influence on the bronchial patency while it was influenced by course treatment. Foridon reduced the lesser and greater circulation pressure. It is recommended to include foridon in the complex treatment of patients with chronic obstructive pulmonary diseases complicated by pulmonary hypertension.
对32例慢性阻塞性肺疾病(慢性阻塞性支气管炎、支气管哮喘)患者采用无创方法(心动描记法、呼吸流速测量法、血压测量法),研究福里多(钙拮抗剂)在单次给药和疗程治疗期间对支气管通畅度、小循环和大循环动脉压的影响。单次给药对支气管通畅度无影响,但疗程治疗有影响。福里多降低了小循环和大循环压力。建议将福里多纳入慢性阻塞性肺疾病合并肺动脉高压患者的综合治疗中。