Division of Biological Resources and Development, Analytic Research Center for Experimental Science, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Biogerontology. 2012 Aug;13(4):439-43. doi: 10.1007/s10522-012-9388-1. Epub 2012 Jul 3.
The life span and survival parameters of the common marmoset (Callithrix jacchus) in a breeding colony at CLEA Japan, Inc. were investigated. The average life span of male marmosets was 148.5 ± 6.1 (mean ± SE) months of age (M), which was significantly longer (P < 0.01) than that of females (111.7 ± 6.0 M). Additionally, the male population reached 25-, 50-, 75- and 90 %-mortality at an older age than the female population. However, the maximum life span in males (259.9 M) was shorter than in females (262.5 M). The survival of females shows a relatively continuous decline; however, the male marmosets show a slight decline in survival during the first 7-9 years and then a dramatic decrease and another slight decline after 14-16 year of age in survival, i.e., a lifespan curve similar to what is observed in colonies of aging rodents and humans. The sex-associated difference in life span was caused by reproductive burden on the females. The present study reported a longer than expected life span of the marmoset, and a long-lived animal can be a powerful model for senescence and longevity sciences.
在 CLEA 日本公司的一个繁殖群体中，对普通狨猴（Callithrix jacchus）的寿命和生存参数进行了研究。雄性狨猴的平均寿命为 148.5 ± 6.1 月龄（M），明显长于雌性（111.7 ± 6.0 M）（P < 0.01）。此外，雄性群体达到 25%、50%、75%和 90%死亡率的年龄比雌性群体更大。然而，雄性的最大寿命（259.9 M）短于雌性（262.5 M）。雌性的生存曲线呈相对连续下降趋势；然而，雄性狨猴在 7-9 岁之前的生存曲线略有下降，然后在 14-16 岁后急剧下降，然后再次略有下降，即与衰老啮齿动物和人类群体中观察到的寿命曲线相似。寿命的性别差异是由雌性的生殖负担引起的。本研究报告了狨猴比预期更长的寿命，而长寿动物可以成为衰老和长寿科学的有力模型。
