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本文引用的文献

1
Fidaxomicin versus vancomycin for Clostridium difficile infection. fidaxomicin 与万古霉素治疗艰难梭菌感染。
N Engl J Med. 2011 Feb 3;364(5):422-31. doi: 10.1056/NEJMoa0910812.
2
Matching methods for causal inference: A review and a look forward.因果推断的匹配方法:综述与展望
Stat Sci. 2010 Feb 1;25(1):1-21. doi: 10.1214/09-STS313.
3
Multicenter study of Clostridium difficile infection rates from 2000 to 2006.多中心研究艰难梭菌感染率 2000 年至 2006 年。
Infect Control Hosp Epidemiol. 2010 Oct;31(10):1030-7. doi: 10.1086/656245.
4
Older patients in the emergency department: a review.急诊科老年患者:综述。
Ann Emerg Med. 2010 Sep;56(3):261-9. doi: 10.1016/j.annemergmed.2010.04.015.
5
Potentially preventable emergency department visits by nursing home residents: United States, 2004.美国疗养院居民可预防的急诊科就诊情况:2004年
NCHS Data Brief. 2010 Apr(33):1-8.
6
Development of a tool for prediction of falls in rehabilitation settings (Predict_FIRST): a prospective cohort study.开发一种用于预测康复环境中跌倒的工具(Predict_FIRST):一项前瞻性队列研究。
J Rehabil Med. 2010 May;42(5):482-8. doi: 10.2340/16501977-0550.
7
Economic healthcare costs of Clostridium difficile infection: a systematic review.艰难梭菌感染的经济医疗成本:系统评价。
J Hosp Infect. 2010 Apr;74(4):309-18. doi: 10.1016/j.jhin.2009.10.016. Epub 2010 Feb 12.
8
Treatment with monoclonal antibodies against Clostridium difficile toxins.针对艰难梭菌毒素的单克隆抗体治疗。
N Engl J Med. 2010 Jan 21;362(3):197-205. doi: 10.1056/NEJMoa0907635.
9
The National Nursing Home Survey: 2004 overview.《国家疗养院调查:2004年概述》
Vital Health Stat 13. 2009 Jun(167):1-155.
10
Understanding the prevalence of inpatient falls associated with toileting in adult acute care settings.了解成人急性护理环境中与如厕相关的住院患者跌倒发生率。
J Nurs Care Qual. 2010 Jan-Mar;25(1):22-30. doi: 10.1097/NCQ.0b013e3181afa321.

艰难梭菌对医疗体系的负担。

Burden of Clostridium difficile on the healthcare system.

机构信息

Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

出版信息

Clin Infect Dis. 2012 Aug;55 Suppl 2(Suppl 2):S88-92. doi: 10.1093/cid/cis335.

DOI:10.1093/cid/cis335
PMID:22752870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3388018/
Abstract

There are few high-quality studies of the costs of Clostridium difficile infection (CDI), and the majority of studies focus on the costs of CDI in acute-care facilities. Analysis of the best available data, from 2008, indicates that CDI may have resulted in $4.8 billion in excess costs in US acute-care facilities. Other areas of CDI-attributable excess costs that need to be investigated are costs of increased discharges to long-term care facilities, of CDI with onset in long-term care facilities, of recurrent CDI, and of additional adverse events caused by CDI.

摘要

关于艰难梭菌感染(CDI)的成本,高质量的研究甚少,且大多数研究都集中在急性护理机构中 CDI 的成本上。对 2008 年最佳可用数据的分析表明,CDI 可能导致美国急性护理机构的超额成本达到 48 亿美元。需要进一步研究的其他与 CDI 相关的超额成本领域包括:长期护理机构中 CDI 发病的成本、长期护理机构中 CDI 的复发成本、以及由 CDI 引起的其他不良事件的成本。