IRCCS-University Hospital San Martino, Genoa, Italy.
Allergy Asthma Immunol Res. 2012 Jul;4(4):171-7. doi: 10.4168/aair.2012.4.4.171. Epub 2012 Feb 8.
The nose and lung are both part of the respiratory tract. Often the diseases affecting the nose and/or the bronchi are treated separately. However, in recent years, numerous studies have highlighted the fact that the respiratory system is a single entity and the concept of "united airway disease" has become more and more important. The unity of the respiratory tract is confirmed both from a morphological and from a functional point of view. Nevertheless, this concept is also confirmed for the respiratory immune system, innervation and vascularization interesting all along the tract, from the nose to the bronchioles. When treating rhinitis, it is often necessary to assess the presence of asthma. Patients with sinusitis should be evaluated for a possible concomitant asthma. Conversely, patients with asthma should always be evaluated for possible nasal disease. The medications that treat nasal diseases appear to be useful in improving control of asthma and in reducing bronchial hyperresponsiveness as well. Physicians should always keep these notions in mind, and evaluate and treat respiratory diseases taking into account the unity of the respiratory tract.
鼻子和肺均属于呼吸道的一部分。通常,影响鼻子和/或支气管的疾病是分开治疗的。然而,近年来,大量研究强调了这样一个事实,即呼吸系统是一个整体,“联合气道疾病”的概念变得越来越重要。从形态学和功能学的角度均证实了呼吸道的统一性。然而,这种概念同样适用于整个呼吸道的呼吸免疫系统、神经支配和血管化,从鼻腔到细支气管均如此。治疗鼻炎时,通常需要评估哮喘的存在。鼻窦炎患者应评估是否同时患有哮喘。相反,哮喘患者也应始终评估是否存在鼻部疾病。治疗鼻部疾病的药物似乎可改善哮喘控制,并降低支气管高反应性。医生应始终牢记这些概念,并在评估和治疗呼吸道疾病时考虑到呼吸道的统一性。