Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Jilin Provincial Key Laboratory of Precise Diagnosis and Treatment of Upper Airway Allergic Diseases, China.
J Immunol Res. 2022 Jul 12;2022:4351345. doi: 10.1155/2022/4351345. eCollection 2022.
Allergic rhinitis is a global illness that puzzles many researchers. Most patients with allergic rhinitis also have lower airway hyperresponsiveness, and an allergic rhinitis attack can increase lower airway hyperresponsiveness. However, the mechanism of the effect of allergic rhinitis on the lower airways is still unclear. In this paper, the effects of allergic rhinitis on the lower airways are studied in terms of epidemiology, anatomy, pathophysiology, nasal function loss, inflammation drainage, nasobronchial reflex, and whole-body circulatory flow to determine the mechanism involved and provide ideas for future diagnosis, treatment, and experiments.
变应性鼻炎是一种令许多研究人员感到困惑的全球性疾病。大多数变应性鼻炎患者也存在下气道高反应性，变应性鼻炎发作可增加下气道高反应性。然而，变应性鼻炎对下气道影响的机制尚不清楚。本文从流行病学、解剖学、病理生理学、鼻功能丧失、炎症引流、鼻支气管反射以及全身循环血流等方面研究变应性鼻炎对下气道的影响，以明确其中涉及的机制，为今后的诊断、治疗和实验提供思路。
