Tüfek Adnan, Yildirim Besir, Tokgöz Orhan, Karaman Haktan, Celik Feyzi, Aycan Ilker Ongüç
Dicle University Medical School, Department of Anesthesiology and Reanimasyon, Diyarbakir, Turkey.
J Pak Med Assoc. 2012 Jun;62(6):609-11.
Many drugs used in anaesthesia have some potential fatal consequences; for example complete heart block and Q-Tc interval prolongation. Since the parasympathetic system in children is not fully developed, electrical transmission of the heart is not stable. Neostigmine is used in order to reverse neuromuscular block but it may also lead to prolongation of Q-Tc interval. We present a case of an 18-month-old male patient weighing 12kg subjected to a surgical operation because of congenital glaucoma. In order to reverse neuromuscular block at the end of operation, atropine and neostigmine were injected intravenously. However, cardiac arrest developed immediately after administration.
许多麻醉中使用的药物都有一些潜在的致命后果；例如完全性心脏传导阻滞和Q-Tc间期延长。由于儿童的副交感神经系统尚未完全发育，心脏的电传导不稳定。新斯的明用于逆转神经肌肉阻滞，但它也可能导致Q-Tc间期延长。我们报告一例18个月大、体重12公斤的男性患者，因先天性青光眼接受手术。为了在手术结束时逆转神经肌肉阻滞，静脉注射了阿托品和新斯的明。然而，给药后立即发生了心脏骤停。
