一名肾衰竭儿童在使用新斯的明后出现Ⅰ型二度房室传导阻滞。
Type I second-degree AV block after neostigmine administration in a child with renal failure.
作者信息
Webb M D
机构信息
Department of Pediatric Dentistry, Baylor College of Dentistry, Dallas, Texas 75246, USA.
出版信息
Anesth Prog. 1995;42(1):21-2.
Abstract
Neostigmine is commonly used to reverse neuromuscular blockade. A side effect can be parasympathetic stimulation, which may result in heart block. Renal failure can decrease the clearance and increase the half-life of the drug, thus increasing the likelihood of a vagomimetic response. A case is presented where a child with renal failure developed a type I second-degree heart block after neostigmine was given.
摘要
新斯的明常用于逆转神经肌肉阻滞。其副作用可能是副交感神经刺激，这可能导致心脏传导阻滞。肾衰竭会降低药物清除率并延长其半衰期，从而增加拟迷走神经反应的可能性。本文介绍了一例肾衰竭患儿在使用新斯的明后发生I型二度心脏传导阻滞的病例。
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本文引用的文献
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Reversal of neuromuscular blockade.
Anesthesiology. 1992 Oct;77(4):785-805. doi: 10.1097/00000542-199210000-00025.
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