对一个疑似癌症高风险家族的调查。
Investigation of a family suspected of being at high risk for cancer.
作者信息
Elwood J M, Crawford G M, Werner M
出版信息
Can Med Assoc J. 1979 Sep 8;121(5):559-63.
Abstract
The investigation of the family of a patient with bilateral breast cancer is described. By means of interviews and the checking of hospital records and death certificates, information was obtained on 199 family members over five generations, 19 of whom had cancer. Comparison with expected numbers of cases showed an excess in only one generation. The interpretation of these findings and the advice given to family members are discussed.
摘要
本文描述了对一名双侧乳腺癌患者家族的调查。通过访谈以及查阅医院记录和死亡证明，获取了五代199名家庭成员的信息，其中19人患有癌症。与预期病例数相比，仅在一代中出现了超额情况。本文讨论了这些研究结果的解读以及向家庭成员提供的建议。
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