Markov Iu G, Berzin' N I
Arkh Anat Gistol Embriol. 1990 Sep;99(9):25-30.
By means of histochemical revealing of zinc and applying radioactive isotope 65Zn accumulation, absorption and distribution of cations of this metal in the mucous membrane of the iliac intestine have been studied in chicken, normal, at ischemia and at A-avitaminosis. An essential zinc-depositing ability is peculiar to coverings of mucus upon the intestine epithelium, and among intracellular components--to smooth endoplasmic reticulum. A-avitaminosis and especially ischemia result in increasing permeability of the apical part of the external membrane of epitheliocytes, in overloading of the latter with zinc cations, when they are introduced into the intestine, as well as in decreasing transepithelial transport of zinc. The changes mentioned are accompanied with certain disturbances in the barrier function of the intestinal epithelium.
通过锌的组织化学显示以及应用放射性同位素⁶⁵Zn积累，研究了正常、缺血和维生素A缺乏状态下鸡回肠黏膜中该金属阳离子的吸收、分布情况。肠上皮黏液覆盖物具有显著的锌沉积能力，细胞内成分中——滑面内质网也有此能力。维生素A缺乏尤其是缺血会导致上皮细胞外膜顶端部分通透性增加，当锌阳离子被引入肠道时，上皮细胞会被锌阳离子过度负载，同时锌的跨上皮运输减少。上述变化伴随着肠上皮屏障功能的某些紊乱。
