Maurizi M, Almadori G, Paludetti G, Ottaviani F, Rosignoli M, Luciano R
Institute of Otorhinolaryngology, Catholic University of the Sacred Heart, Rome, Italy.
Audiology. 1990;29(6):322-8. doi: 10.3109/00206099009072863.
The authors investigated the 40-Hz steady-state responses (SSR) in 32 full-term newborns and in 10 normal children (5-8 years old), using 500-Hz tone bursts. The 40-Hz SSR threshold is located at about 50 and 30 dB nHL in newborns and older children, respectively. The latencies of both P1 and N1 waves decreased significantly with age, while the amplitudes increased. No significant latency and amplitude intersex differences have been observed. Moreover, with age, the 40-Hz SSR became more stable, their test-retest replicability improved, and P1-N1 wave occurrence increased. The authors finally discuss the possible underlying mechanisms of these findings and conclude that the 40-Hz SSR are difficult to obtain and are scarcely reliable in defining the low-frequency threshold in newborns. The stability and reliability of the responses increase with age, and the electrophysiological and behavioral thresholds to low-frequency stimuli tend to overlap.
作者使用500赫兹短纯音，对32名足月新生儿和10名正常儿童（5 - 8岁）的40赫兹稳态反应（SSR）进行了研究。40赫兹SSR阈值在新生儿和大龄儿童中分别约为50分贝听力级（dB nHL）和30分贝听力级。P1波和N1波的潜伏期均随年龄显著缩短，而波幅则增大。未观察到潜伏期和波幅存在显著的性别差异。此外，随着年龄增长，40赫兹SSR变得更加稳定，重测可重复性提高，P1 - N1波的出现增加。作者最后讨论了这些发现可能的潜在机制，并得出结论：40赫兹SSR难以获得，在确定新生儿低频阈值方面几乎不可靠。反应的稳定性和可靠性随年龄增加，低频刺激的电生理阈值和行为阈值趋于重叠。
