McSweeney Jean, Pettey Christina, Lefler Leanne L, Heo Seongkum
College of Nursing, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Womens Health (Lond). 2012 Jul;8(4):473-85. doi: 10.2217/whe.12.22.
This article reviews literature pertinent to cardiovascular disparities in women, focusing primarily on heart failure (HF). It provides an in-depth look at causes, biological influences, self-management and lack of adherence to HF-treatment guidelines in women. Disparities in treatment of causative factors of HF, such as myocardial infarction and hypertension, contribute to women having poorer HF outcomes than men. This article discusses major contributing reasons for nonadherence to medication regimes for HF in women, including advanced age at time of diagnosis, likelihood of multiple comorbidities, lack of social support and low socioeconomic status. Limited inclusion of women in clinical trials and the scarcity of gender analyses for HF and other cardiovascular diseases continues to limit the applicability of research findings to women.
本文回顾了与女性心血管疾病差异相关的文献，主要聚焦于心力衰竭（HF）。它深入探讨了女性心力衰竭的病因、生物学影响、自我管理以及对心力衰竭治疗指南的依从性不足。心力衰竭病因因素（如心肌梗死和高血压）治疗方面的差异导致女性心力衰竭的预后比男性更差。本文讨论了女性不坚持心力衰竭药物治疗方案的主要原因，包括诊断时年龄较大、多种合并症的可能性、缺乏社会支持以及社会经济地位较低。临床试验中女性纳入有限，以及心力衰竭和其他心血管疾病性别分析的匮乏，继续限制了研究结果对女性的适用性。
