Center for Health Services Research in Primary Care, Durham VAMC, Durham, NC, USA.
Am Heart J. 2011 Sep;162(3):412-24. doi: 10.1016/j.ahj.2011.06.007.
Poor adherence to efficacious cardiovascular-related medications has led to considerable morbidity, mortality, and avoidable health care costs. This article provides results of a recent think-tank meeting in which various stakeholder groups representing key experts from consumers, community health providers, the academic community, decision-making government officials (Food and Drug Administration, National Institutes of Health, etc), and industry scientists met to evaluate the current status of medication adherence and provide recommendations for improving outcomes. Below, we review the magnitude of the problem of medication adherence, prevalence, impact, and cost. We then summarize proven effective approaches and conclude with a discussion of recommendations to address this growing and significant public health issue of medication nonadherence.
由于对有效心血管相关药物的依从性差,导致了相当大的发病率、死亡率和可避免的医疗保健费用。本文提供了最近一次智库会议的结果,来自消费者、社区卫生提供者、学术界、决策政府官员(食品和药物管理局、美国国立卫生研究院等)和工业科学家的各利益相关者群体的代表参加了会议,评估了药物依从性的现状,并为改善结果提出了建议。下面,我们回顾一下药物依从性问题的严重程度、普遍性、影响和成本。然后,我们总结了经过验证的有效方法,并以讨论解决这一日益严重的重大公共卫生问题的建议作为结论。