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一种简单的糖尿病血管严重程度分期工具及其在澳大利亚北部托雷斯海峡岛民和原住民成年人群中的应用。

A simple diabetes vascular severity staging instrument and its application to a Torres Strait Islander and Aboriginal adult cohort of north Australia.

机构信息

Health Economics and Social Policy Group, Division of Health Sciences, University of South Australia, Adelaide, 5001, Australia.

出版信息

BMC Health Serv Res. 2012 Jul 3;12:185. doi: 10.1186/1472-6963-12-185.

Abstract

BACKGROUND

To develop an instrument that predicts diabetes-related vascular disease severity using routinely collected data on Australian Aboriginal and Torres Strait Islander adults with type 2 diabetes, in the absence of diabetes duration.

METHODS

A complex diabetes severity classification system was simplified and adapted for use with an Australian Aboriginal and Torres Strait Islander adult population with type 2 diabetes in north Queensland. Detailed vascular health risks and morbidities were mapped to routinely collected measures. Individual-level health screening, hospital separation and mortality data were linked and used to plot mean monthly in-patient hospital cost and percent mortality by disease severity as defined by the newly developed instrument, to test construct validity.

RESULTS

The revised instrument consists of four combined diabetes-related microvascular and macrovascular stages that range from least severe (stage 1) to severe irreversible vascular impairment (stage 4). When applied to data of an Aboriginal and Torres Strait Islander Australian population the instrument showed good construct validity, predicting higher hospital cost and mortality as vascular disease severity increased.

CONCLUSIONS

This instrument discriminates between levels of diabetes-related vascular disease severity, displays good construct validity by predicting increased hospital cost and mortality with worsening severity and can be populated with routinely collected data. It may assist with future health service research and its use could be extended to practice settings for health care planning for diabetes management programs and monitoring vascular disease progression.

摘要

背景

本研究旨在开发一种工具,通过对澳大利亚原住民和托雷斯海峡岛民 2 型糖尿病患者的常规数据进行分析,预测其糖尿病相关血管疾病的严重程度,同时无需考虑糖尿病病程。

方法

本研究简化并改编了一种复杂的糖尿病严重程度分类系统,使之适用于北昆士兰州的澳大利亚原住民和托雷斯海峡岛民 2 型糖尿病患者。详细的血管健康风险和并发症被映射到常规收集的指标中。个体层面的健康筛查、住院分离和死亡率数据被链接起来,用于绘制新开发工具定义的疾病严重程度的平均每月住院费用和死亡率,以检验构建效度。

结果

修订后的工具包含四个联合的糖尿病相关微血管和大血管阶段,范围从最轻微(阶段 1)到严重的不可逆血管损伤(阶段 4)。当应用于澳大利亚原住民和托雷斯海峡岛民的人群数据时,该工具表现出良好的构建效度,随着血管疾病严重程度的增加,预测更高的住院费用和死亡率。

结论

该工具可区分糖尿病相关血管疾病的严重程度,通过预测严重程度增加导致的住院费用增加和死亡率增加,显示出良好的构建效度,并且可以用常规收集的数据进行填充。它可能有助于未来的卫生服务研究,并且可以将其应用于实践环境,用于糖尿病管理计划的医疗保健规划和监测血管疾病的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c2/3409067/e74e6ef8c558/1472-6963-12-185-1.jpg

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