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有关十溴二苯醚(decaBDE)和六溴环十二烷(HBCD)对人类健康风险的专家评估的政策相关结果。

Policy relevant results from an expert elicitation on the human health risks of decabromodiphenyl ether (decaBDE) and hexabromocyclododecane (HBCD).

机构信息

Norwegian Veterinary Institute, POBox 750, 0106 Oslo, Norway.

出版信息

Environ Health. 2012 Jun 28;11 Suppl 1(Suppl 1):S7. doi: 10.1186/1476-069X-11-S1-S7.

DOI:10.1186/1476-069X-11-S1-S7
PMID:22759507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3388476/
Abstract

AIM

Apply a recently developed expert elicitation procedure to evaluate the state of the current knowledge of the two brominated flame retardants (BFRs) most commonly used today; decabromo-diphenyl ether (decaBDE) and hexabromocyclododecane (HBCD) and their potential impact on human health in order to support policy considerations. This expert elicitation was organized by the HENVINET (Health and Environment Network) Consortium.

METHOD

The HENVINET expert elicitation procedure that was used in the evaluations of decaBDE and HBCD is a rapid assessment tool aimed at highlighting areas of agreement and areas of disagreement on knowledge-related key issues for environment and health policy decision making.

RESULTS

The outcome of the expert consultation on BFRs was concrete expert advice for policy makers with specific priorities for further action made clear for both stakeholders and policy makers. The experts were not in agreement whether or not the knowledge currently available on decaBDE or HBCD is sufficient to justify policy actions, but most experts considered that enough data already exists to support a ban or restriction on the use of these compounds. All experts agreed on the necessity of more research on the compounds. Priority issues for further research were, among others:• more studies on the extent of human exposure to the compounds.• more studies on the fate and concentration in the human body of the compounds.

摘要

目的

应用最近开发的专家评估程序来评估目前最常用的两种溴化阻燃剂(BFRs)——十溴二苯醚(decaBDE)和六溴环十二烷(HBCD)的知识现状及其对人类健康的潜在影响,以支持政策考虑。这项专家评估是由 HENVINET(健康与环境网络)联盟组织的。

方法

在评估 decaBDE 和 HBCD 时,HENVINET 使用的专家评估程序是一种快速评估工具,旨在突出与环境和健康政策决策相关的知识关键问题上的共识和分歧领域。

结果

BFRs 专家咨询的结果为政策制定者提供了具体的专家建议,并为利益相关者和政策制定者明确了进一步行动的优先事项。专家们对于目前关于 decaBDE 或 HBCD 的知识是否足以证明采取政策行动的说法存在分歧,但大多数专家认为,已经存在足够的数据来支持对这些化合物的禁用或限制。所有专家都认为有必要对这些化合物进行更多的研究。进一步研究的优先事项包括:

  1. 更多关于人类接触这些化合物的程度的研究。

  2. 更多关于这些化合物在人体内的归宿和浓度的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/284b0af1e061/1476-069X-11-S1-S7-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/880faeedb228/1476-069X-11-S1-S7-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/ffa851d8c9eb/1476-069X-11-S1-S7-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/284b0af1e061/1476-069X-11-S1-S7-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/880faeedb228/1476-069X-11-S1-S7-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/ffa851d8c9eb/1476-069X-11-S1-S7-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e47/3388476/284b0af1e061/1476-069X-11-S1-S7-3.jpg

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2
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Environ Health. 2012 Jun 28;11 Suppl 1(Suppl 1):S3. doi: 10.1186/1476-069X-11-S1-S3.
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The use of expert elicitation in environmental health impact assessment: a seven step procedure.
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专家 elicitation 在环境健康影响评估中的应用:七步骤程序。
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Reproductive and developmental toxicity of phthalates.邻苯二甲酸酯的生殖和发育毒性。
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Neurodevelopmental effects of decabromodiphenyl ether (BDE-209) and implications for the reference dose.十溴二苯醚(BDE-209)的神经发育效应及其对参考剂量的影响
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