Department of Orthopaedic Surgery, Shanghai Fengxian Central Hospital, No. 9588, NanFeng Road, Fengxian District, Shanghai 201400, China.
Molecules. 2012 Jul 3;17(7):8001-9. doi: 10.3390/molecules17078001.
Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats.
许多常见的食用食物、草药和香料都含有复杂的天然生物活性分子，称为植物化学物质，这些物质可能对健康有益。在这项研究中，评估了六味壮骨颗粒（LWZGG）对骨质疏松症发展过程中矿物质代谢的影响。结果表明，血清雌激素、骨钙素（BGP）和降钙素（CT）水平、骨钙、锌和铜水平、股骨、腰椎和小梁骨密度、胫骨最大应力和最大弯曲强度增加，而血清甲状旁腺激素（PTH）、血清和尿钙、锌和铜水平降低。可以得出结论，LWZGG 可有效改善去卵巢（OVX）大鼠的骨质量。
