Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Clin Pharmacol Ther. 2012 Aug;92(2):170-81. doi: 10.1038/clpt.2012.85. Epub 2012 Jul 4.
In the poorest regions of the United States, especially along the Gulf Coast and in South Texas, are a group of endemic parasitic and related infections known as the neglected infections of poverty. Such infections are characterized by their chronicity, disabling features, and disproportionate impact on the estimated 46 million people who live below the U.S. poverty line. Today more Americans live in poverty than ever before in the half-century that the Census Bureau has been recording poverty rates. In association with that poverty, a group of major neglected infections of poverty have emerged in the United States. Here we describe the major neglected infections of poverty in the United States, with a brief overview of their significant epidemiological features, their links with poverty, and our approaches to their diagnosis, management, and treatment.
在美国最贫困的地区,尤其是墨西哥湾沿岸和南得克萨斯州,存在一组被称为贫困相关被忽视感染的地方性寄生虫和相关感染。这些感染的特点是慢性、致残性以及对估计有 4600 万生活于美国贫困线以下的人群产生不成比例的影响。在人口普查局记录贫困率的半个世纪以来,如今生活于贫困中的美国人比以往任何时候都多。伴随着贫困,一组主要的贫困相关被忽视感染在美国出现。在这里,我们描述了美国的主要贫困相关被忽视感染,简要概述了它们的重要流行病学特征、与贫困的联系以及我们对其诊断、管理和治疗的方法。