李斯特菌单核细胞增生症性脑膜炎在免疫功能正常成人中的一例报告。

Listeria monocytogenes meningitis in an immunocompetent adult: a case report.

机构信息

Department of Infectious Diseases, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

出版信息

Rev Soc Bras Med Trop. 2012 Jun;45(3):410-1. doi: 10.1590/s0037-86822012000300028.

DOI:10.1590/s0037-86822012000300028

PMID:22760149

Abstract

Listeria monocytogenes (L. monocytogenes) is an uncommon cause of bacterial meningitis in immunocompetent adults. Patients with immunosuppression are at increased risk of developing serious invasive diseases, particularly meningitis. We describe a case of meningitis caused by L. monocytogenes in an immunocompetent and previously healthy 34-year-old adult. The patient received treatment with intravenous ampicillin plus amikacin and made a full recovery. L. monocytogenes should be suspected in immunocompetent adults with bacterial meningitis who fail to respond to empirical antibiotic treatment.

摘要

李斯特菌（L. monocytogenes）是一种在免疫功能正常的成年人中罕见的细菌性脑膜炎致病菌。免疫抑制患者发生严重侵袭性疾病（特别是脑膜炎）的风险增加。我们描述了一例免疫功能正常且既往健康的 34 岁成年患者由李斯特菌引起的脑膜炎。该患者接受了氨苄西林联合阿米卡星静脉治疗，并完全康复。对于经验性抗生素治疗无效的免疫功能正常的细菌性脑膜炎成人，应怀疑李斯特菌感染。