Mandigers L, Epker J L
Erasmus Medical Center Rotterdam The Netherlands, Intensive Care Unit - Adults, Rotterdam, The Netherlands.
BMC Clin Pathol. 2018 Dec 27;18:15. doi: 10.1186/s12907-018-0083-2. eCollection 2018.
is a bacterium present in some food products. It is rarely the cause of Rhombencephalitis in immunocompetent patients.
We report a case of an immunocompetent patient, presenting with progressive perioral numbness and dizziness. Despite treatment with antiplatelet drugs, antiviral medication, antibiotics and corticosteroids for a wide differential diagnosis, the patient deteriorated tremendously. Eventually the patient died of Listeria rhombencephalitis, most likely due to the late diagnosis and concomitant late initiation of antibiotics combined with badly timed and inappropriate corticosteroid prescription.
Early adequate antibiotic treatment is essential in Listeria rhombencephalitis and corticosteroid therapy should be avoided when Listeriosis is suspected.
是一种存在于某些食品中的细菌。在免疫功能正常的患者中，它很少是引起菱脑炎性的病因。
我们报告一例免疫功能正常的患者，表现为进行性口周麻木和头晕。尽管针对广泛的鉴别诊断使用了抗血小板药物、抗病毒药物、抗生素和皮质类固醇进行治疗，但患者病情急剧恶化。最终，该患者死于李斯特菌性菱脑炎，很可能是由于诊断延迟以及抗生素开始使用过晚，再加上皮质类固醇处方时机不当和不合适。
在李斯特菌性菱脑炎中，早期充分的抗生素治疗至关重要，并且在怀疑李斯特菌病时应避免使用皮质类固醇疗法。
