Zanetta Adrián, Cuestas Giselle, Méndez Venditto Nicolás, Rodríguez Hugo, Tiscornia Carlos, Magaró Manuel, Magaró Salvador
Servicio de Endoscopia Respiratoria, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.
Arch Argent Pediatr. 2012 May-Jun;110(3):e39-42. doi: 10.5546/aap.2012.e39.
Squamous cell carcinoma of the larynx is very rare in children and adolescents. It is usually diagnosed at late stages because early symptoms are often attributed to the maturation process or other common laryngeal pediatric diseases. Early visualization of vocal cords with fexible laryngoscopy is important in children presenting suggestive symptoms of laryngeal pathology. Defnitive diagnosis of carcinoma is made by biopsy, and juvenile laryngeal papillomatosis the most important differential diagnosis. Treatment constitutes a clinical challenge. There are no established protocols, and clinicians should make a special effort to preserve the functions of the larynx, and avoid long term complications. We present a 12-years-old child with invasive laryngeal carcinoma, without prior history of juvenile papillomatosis or radiotherapy, which responded favorably to chemotherapy and radiotherapy.
喉鳞状细胞癌在儿童和青少年中非常罕见。它通常在晚期才被诊断出来，因为早期症状常常被归因于发育过程或其他常见的小儿喉部疾病。对于出现喉部病变提示症状的儿童，通过灵活喉镜早期观察声带很重要。癌的确诊依靠活检，而青少年喉乳头状瘤病是最重要的鉴别诊断。治疗是一项临床挑战。目前尚无既定方案，临床医生应特别努力保留喉部功能，并避免长期并发症。我们报告一名12岁的侵袭性喉癌患儿，既往无青少年乳头状瘤病或放疗史，该患儿对化疗和放疗反应良好。
