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壶腹癌的皮肤复发:一种不寻常的表现。

Cutaneous relapse of an ampullary carcinoma: an unusual presentation.

作者信息

Lamarca Angela, Martinez-Marin Virginia, Feliu Jaime

机构信息

Department of Medical Oncology, H U La Paz, Madrid, Spain.

出版信息

BMJ Case Rep. 2012 Jul 3;2012:bcr0120125580. doi: 10.1136/bcr.01.2012.5580.

Abstract

This is the first ever reported case about a cutaneous relapse of small bowel adenocarcinoma. The ampulla of Vater is the area of the small bowel that presents more frequently malignant transformation, nevertheless ampullary adenocarcinomas are rare but aggressive diseases. However, distant metastases are infrequent. Cutaneous metastases constitute the 5.3% of skin tumours, and are usually found in the 12% of malignancies. Their management usually includes local treatment if they are unique and systemic treatment when they are multiple. Chemotherapy schemes used in ampullary adenocarcinoma are those used in cholangiocarcinomas, pancreas and tumours of the gallbladder; nevertheless, given the intestinal origin of these tumours combinations of capecitabine and oxaliplatin are commonly used.

摘要

这是首次报道的小肠腺癌皮肤复发病例。十二指肠乳头是小肠中恶性转化更频繁出现的部位,然而壶腹腺癌虽罕见但侵袭性强。不过,远处转移并不常见。皮肤转移瘤占皮肤肿瘤的5.3%,通常在12%的恶性肿瘤中出现。其治疗通常包括单个转移瘤时的局部治疗以及多个转移瘤时的全身治疗。用于壶腹腺癌的化疗方案与用于胆管癌、胰腺癌和胆囊肿瘤的方案相同;然而,鉴于这些肿瘤的肠道起源,通常使用卡培他滨和奥沙利铂的联合方案。

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