多形性恶性组织细胞瘤：一名因溃疡性结肠炎服用硫唑嘌呤的患者所患的罕见皮肤癌。
Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis.
作者信息
Sood Ruchi, Daw Hamed A
机构信息
Department of Internal Medicine, Fairview Hospital, Cleveland, Ohio, USA.
出版信息
BMJ Case Rep. 2012 Jul 3;2012:bcr0320125957. doi: 10.1136/bcr.03.2012.5957.
Abstract
A 67-year-old female who was diagnosed with ulcerative colitis in 2001, presented with a soft tissue mass in the middle of her back of 4 months duration in April 2011. It was excised; however it recurred at the same site in September 2011. Wide excision of the mass was done. Pathology revealed T1aNxM0 pleomorphic malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma. Whole body bones scan and staging CT scan of the chest, abdomen and pelvis was negative for distant metastasis. She received local radiotherapy at the site of excision. No chemotherapy was given.
摘要
一名67岁女性，2001年被诊断为溃疡性结肠炎，2011年4月因背部正中出现持续4个月的软组织肿块前来就诊。该肿块被切除；然而，2011年9月在同一部位复发。遂对肿块进行了广泛切除。病理检查显示为T1aNxM0多形性恶性纤维组织细胞瘤或未分化多形性肉瘤。全身骨骼扫描以及胸部、腹部和骨盆的分期CT扫描均未发现远处转移。她在切除部位接受了局部放疗。未进行化疗。
相似文献
1
Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis.多形性恶性组织细胞瘤：一名因溃疡性结肠炎服用硫唑嘌呤的患者所患的罕见皮肤癌。
BMJ Case Rep. 2012 Jul 3;2012:bcr0320125957. doi: 10.1136/bcr.03.2012.5957.
2
Undifferentiated pleomorphic sarcoma: Factors predictive of adverse outcomes.未分化多形性肉瘤：不良预后的预测因素。
J Am Acad Dermatol. 2018 Nov;79(5):853-859. doi: 10.1016/j.jaad.2018.05.022. Epub 2018 May 19.
3
Predicting the prognosis of undifferentiated pleomorphic soft tissue sarcoma: a 20-year experience of 266 cases.未分化多形性软组织肉瘤的预后预测：266例患者的20年经验
ANZ J Surg. 2019 Sep;89(9):1045-1050. doi: 10.1111/ans.15348. Epub 2019 Jul 30.
4
Cutaneous malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma) arising in a chronic scalp ulcer of a patient with non-bullous congenital ichthyosiform erythroderma.发生于非大疱性先天性鱼鳞病样红皮病患者慢性头皮溃疡的皮肤恶性纤维组织细胞瘤（未分化多形性肉瘤）。
J Eur Acad Dermatol Venereol. 2009 Feb;23(2):202-3. doi: 10.1111/j.1468-3083.2008.02780.x. Epub 2008 Apr 23.
5
Malignant fibrous histiocytoma (undifferentiated high-grade pleomorphic sarcoma) occurring in tuberous sclerosis: a case report.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Apr;103(4):e54-9. doi: 10.1016/j.tripleo.2006.05.014. Epub 2006 Sep 26.
6
Generalized Pyoderma Gangrenosum Associated with Ulcerative Colitis: Successful Treatment with Infliximab and Azathioprine.与溃疡性结肠炎相关的泛发性坏疽性脓皮病：英夫利昔单抗和硫唑嘌呤治疗成功
Acta Dermatovenerol Croat. 2016 Apr;24(1):83-5.
7
Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: Updates on Classification and Management.非典型纤维黄色瘤和多形性真皮肉瘤：分类和治疗的最新进展。
Dermatol Clin. 2019 Jul;37(3):253-259. doi: 10.1016/j.det.2019.02.001. Epub 2019 Apr 16.
8
[Retroperitoneal sarcomas: a case of a malignant giant fibrous histiocytoma].[腹膜后肉瘤：1例恶性巨细胞纤维组织细胞瘤]
Chir Ital. 2007 Jul-Aug;59(4):581-5.
9
Pleomorphic sarcoma of the neck.颈部多形性肉瘤
J Craniofac Surg. 2011 Nov;22(6):e51-3. doi: 10.1097/SCS.0b013e318231e281.
10
Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis.溃疡性结肠炎患者在常规结肠镜检查时发现的肛门恶性黑色素瘤。
Korean J Gastroenterol. 2017 Jun 25;69(6):368-371. doi: 10.4166/kjg.2017.69.6.368.
本文引用的文献
1
Skin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repair.器官移植受者的皮肤癌：免疫抑制药物对 DNA 修复的影响。
Exp Dermatol. 2012 Jan;21(1):2-6. doi: 10.1111/j.1600-0625.2011.01413.x.
2
Pleomorphic sarcoma of the neck.颈部多形性肉瘤
J Craniofac Surg. 2011 Nov;22(6):e51-3. doi: 10.1097/SCS.0b013e318231e281.
3
Ulcerative colitis.溃疡性结肠炎
N Engl J Med. 2011 Nov 3;365(18):1713-25. doi: 10.1056/NEJMra1102942.
4
Primary malignant fibrous histiocytoma: a rare case.原发性恶性纤维组织细胞瘤：1例罕见病例。
Case Rep Med. 2011;2011:134801. doi: 10.1155/2011/134801. Epub 2011 Oct 18.
5
Skin cancers associated with autoimmune conditions among elderly adults.老年人与自身免疫性疾病相关的皮肤癌。
Br J Cancer. 2010 Jun 29;103(1):112-4. doi: 10.1038/sj.bjc.6605733. Epub 2010 Jun 15.
6
Increased risk for non-melanoma skin cancer in patients with inflammatory bowel disease.炎症性肠病患者非黑素瘤皮肤癌风险增加。
Clin Gastroenterol Hepatol. 2010 Mar;8(3):268-74. doi: 10.1016/j.cgh.2009.11.024. Epub 2010 Jan 16.
7
Adult head and neck soft tissue sarcomas: treatment and outcome.成人头颈部软组织肉瘤：治疗与预后
Sarcoma. 2008;2008:654987. doi: 10.1155/2008/654987.
8
Immunosuppression, skin cancer, and ultraviolet A radiation.免疫抑制、皮肤癌与紫外线A辐射
N Engl J Med. 2005 Dec 22;353(25):2712-3. doi: 10.1056/NEJMcibr054224.
9
Azathioprine and UVA light generate mutagenic oxidative DNA damage.硫唑嘌呤和紫外线A光会产生诱变的氧化性DNA损伤。
Science. 2005 Sep 16;309(5742):1871-4. doi: 10.1126/science.1114233.
10
Malignant fibrous histiocytoma: outcome of tumours in the head and neck compared with those in the trunk and extremities.恶性纤维组织细胞瘤：头颈部肿瘤与躯干及四肢肿瘤的预后比较。
Br J Oral Maxillofac Surg. 2006 Jun;44(3):209-12. doi: 10.1016/j.bjoms.2005.06.006. Epub 2005 Jul 18.
Zotero 插件