Katsourakis Anastasios, Noussios George, Hadjis Iosif, Evangelou Neofitos, Chatzitheoklitos Efthimios
Department of Surgery, "Agios Dimitrios" General Hospital of Thessaloniki, 54634 Thessaloniki, Greece.
Case Rep Med. 2011;2011:134801. doi: 10.1155/2011/134801. Epub 2011 Oct 18.
Malignant fibrous histiocytoma (MFH) of the small intestine is an extremely rare condition. It occurs most commonly in the extremities and the trunk. We report a case of a 67-year-old woman who admitted with fever, myalgia, and altered status. After thorough investigation, a tumor of the jejunum was found. The patient underwent complete surgical removal of the tumor. A diagnosis of MFN (undifferentiated high-grade pleomorphic sarcoma) was made. The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. MFH of the small intestine is an extremely rare neoplasm with an aggressive biological behaviour. In this paper, pathogenesis, natural history, and treatment are reviewed.
小肠恶性纤维组织细胞瘤（MFH）极为罕见。它最常发生于四肢和躯干。我们报告一例67岁女性，因发热、肌痛和意识状态改变入院。经过全面检查，发现空肠有一个肿瘤。患者接受了肿瘤的完整手术切除。诊断为MFN（未分化高级别多形性肉瘤）。患者接受了吉西他滨辅助化疗。术后两年，患者因疾病复发死亡。小肠MFH是一种具有侵袭性生物学行为的极其罕见的肿瘤。本文对其发病机制、自然病程和治疗进行了综述。
