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本文引用的文献

1
Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment.遗传性血色素沉着症:发病机制、诊断与治疗。
Gastroenterology. 2010 Aug;139(2):393-408, 408.e1-2. doi: 10.1053/j.gastro.2010.06.013. Epub 2010 Jun 11.
2
Role of iron in neurotoxicity: a cause for concern in the elderly?铁在神经毒性中的作用:老年人应关注的一个问题?
Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):22-9. doi: 10.1097/MCO.0b013e32831ba07c.
3
The epidemiology of haemochromatosis: a population-based study.血色病的流行病学:一项基于人群的研究。
Aliment Pharmacol Ther. 2009 Jan;29(2):183-92. doi: 10.1111/j.1365-2036.2008.03874.x. Epub 2008 Oct 20.
4
Haemochromatosis.血色素沉着症
Lancet. 2007 Dec 1;370(9602):1855-60. doi: 10.1016/S0140-6736(07)61782-6.
5
Haemochromatosis: where are all the patients?
Scott Med J. 2001 Aug;46(4):99-100. doi: 10.1177/003693300104600401.
6
Hereditary hemochromatosis: etiologic, pathologic, and clinical aspects.遗传性血色素沉着症:病因、病理及临床方面
Semin Hematol. 1998 Jan;35(1):55-71.
7
Long-term survival in patients with hereditary hemochromatosis.遗传性血色素沉着症患者的长期生存情况。
Gastroenterology. 1996 Apr;110(4):1107-19. doi: 10.1053/gast.1996.v110.pm8613000.
8
Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome.遗传性血色素沉着症:一例基底节铁蓄积伴帕金森综合征病例
J Neurol Neurosurg Psychiatry. 1995 Sep;59(3):318-21. doi: 10.1136/jnnp.59.3.318.
9
Idiopathic hemochromatosis, an interim report.特发性血色素沉着症:一份中期报告
Medicine (Baltimore). 1980 Jan;59(1):34-49. doi: 10.1097/00005792-198001000-00002.

解决棘手问题——血色素沉着症中的认知障碍

Ironing out the rough spots--cognitive impairment in haemochromatosis.

作者信息

Brown Shona, Torrens Lorna A

机构信息

Department of Clinical Psychology, Astley Ainslie Hospital, Edinburgh, UK.

出版信息

BMJ Case Rep. 2012 Jul 3;2012:bcr0320126147. doi: 10.1136/bcr.03.2012.6147.

DOI:10.1136/bcr.03.2012.6147
PMID:22761228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3391393/
Abstract

A man in his late 40s, referred by his general practitioner (GP) to a psychology-led pain management programme, made a subjective and spontaneous report of cognitive impairment. He further mentioned a ten year history of erectile dysfunction, joint pain, occasional nausea and excessive fatigue. He underwent cognitive assessment. Advised to return to his GP to seek further investigation, he was ultimately subsequently diagnosed with haemochromatosis and began radical therapeutic venesection. Repeat cognitive assessment, a year later and following stabilisation of the condition, found improvement on some cognitive measures. Subjective report was of vastly improved cognitive function.

摘要

一名40多岁的男子由他的全科医生转介至一个以心理学为主导的疼痛管理项目,他主观且自发地报告了认知障碍。他还提到有十年勃起功能障碍、关节疼痛、偶尔恶心和过度疲劳的病史。他接受了认知评估。建议他回到全科医生处寻求进一步检查,最终他被诊断为血色素沉着症,并开始进行根治性治疗性静脉切开放血术。一年后,在病情稳定后进行的重复认知评估发现,一些认知指标有所改善。主观报告显示认知功能有了极大改善。