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Conditional gene manipulation: Cre-ating a new biological era.
J Zhejiang Univ Sci B. 2012 Jul;13(7):511-24. doi: 10.1631/jzus.B1200042.
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Road to precision: recombinase-based targeting technologies for genome engineering.
Curr Opin Biotechnol. 2007 Oct;18(5):411-9. doi: 10.1016/j.copbio.2007.07.013. Epub 2007 Sep 27.
3
Strategies for the use of site-specific recombinases in genome engineering.
Methods Mol Med. 2005;103:245-57. doi: 10.1385/1-59259-780-7:245.
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Conditional somatic mutagenesis in the mouse using site-specific recombinases.
Handb Exp Pharmacol. 2007(178):3-28. doi: 10.1007/978-3-540-35109-2_1.
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Progress in gene targeting: using mutant mice to study renal function and disease.
Kidney Int. 2008 Aug;74(4):427-37. doi: 10.1038/ki.2008.146. Epub 2008 Apr 16.
8
Transgene manipulation in zebrafish by using recombinases.
Methods Cell Biol. 2004;77:363-79. doi: 10.1016/s0091-679x(04)77020-x.
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Mammalian genome targeting using site-specific recombinases.
Front Biosci. 2006 Jan 1;11:1108-36. doi: 10.2741/1867.

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An overview of mouse models of hepatocellular carcinoma.
Infect Agent Cancer. 2023 Sep 5;18(1):49. doi: 10.1186/s13027-023-00524-9.
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MicroRNAs Regulating Autophagy in Neurodegeneration.
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Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events.
Sci Adv. 2020 Feb 12;6(7):eaax2941. doi: 10.1126/sciadv.aax2941. eCollection 2020 Feb.
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How technical progress reshaped behavioral neuroendocrinology during the last 50 years… and some methodological remarks.
Horm Behav. 2020 Feb;118:104682. doi: 10.1016/j.yhbeh.2020.104682. Epub 2020 Jan 13.
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Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.
Mol Biol Rep. 2020 Feb;47(2):1381-1391. doi: 10.1007/s11033-019-05214-7. Epub 2019 Dec 12.
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Inverse pharmacology: Approaches and tools for introducing druggability into engineered proteins.
Biotechnol Adv. 2019 Dec;37(8):107439. doi: 10.1016/j.biotechadv.2019.107439. Epub 2019 Sep 5.

本文引用的文献

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A conditional knockout resource for the genome-wide study of mouse gene function.
Nature. 2011 Jun 15;474(7351):337-42. doi: 10.1038/nature10163.
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PhiC31 integrase induces efficient site-specific excision in zebrafish.
Transgenic Res. 2011 Feb;20(1):183-9. doi: 10.1007/s11248-010-9394-5. Epub 2010 Jun 17.
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Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors.
PLoS One. 2010 Mar 24;5(3):e9846. doi: 10.1371/journal.pone.0009846.
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A review of current large-scale mouse knockout efforts.
Genesis. 2010 Feb;48(2):73-85. doi: 10.1002/dvg.20594.
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Transgene excision in zebrafish using the phiC31 integrase.
Genesis. 2010 Feb;48(2):137-43. doi: 10.1002/dvg.20595.
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Conditional RNAi: towards a silent gene therapy.
Adv Drug Deliv Rev. 2009 Jul 2;61(7-8):650-64. doi: 10.1016/j.addr.2009.03.016. Epub 2009 Apr 24.
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Creation and use of a cre recombinase transgenic database.
Methods Mol Biol. 2009;530:365-78. doi: 10.1007/978-1-59745-471-1_19.
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Regulated gene insertion by steroid-induced PhiC31 integrase.
Nucleic Acids Res. 2008 Jun;36(11):e67. doi: 10.1093/nar/gkn298. Epub 2008 May 22.
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EUCOMM--the European conditional mouse mutagenesis program.
Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5. doi: 10.1093/bfgp/elm022. Epub 2007 Oct 29.
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Controlled expression of transgenes introduced by in vivo electroporation.
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1027-32. doi: 10.1073/pnas.0610155104. Epub 2007 Jan 5.

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