Trovik Clement S, Skjeldal Sigmund, Bauer Henrik, Rydholm Anders, Jebsen Nina
Musculoskeletal Tumour Center, Department of Orthopedics/Oncology, Haukeland University Hospital, 5021 Bergen, Norway.
Sarcoma. 2012;2012:290698. doi: 10.1155/2012/290698. Epub 2012 Jun 18.
Surgery remains the mainstay of soft tissue sarcoma (STS) treatment and has been the primary treatment for the majority of patients in Scandinavia during the last 30 years although the use of adjuvant radiotherapy has increased. Patient and treatment characteristics have been recorded in the Scandinavian Sarcoma Group (SSG) Register since 1987. When the effect of new radiotherapy guidelines from 1998 was evaluated, the reliability of surgical margin assessments among different Scandinavian institutions was investigated. Margins were reevaluated by a panel of sarcoma surgeons, studying pathology and surgical reports from 117 patients, randomly selected among 470 recorded patients treated between 1998-2003. In 80% of cases, the panel agreed with the original classification. Disagreement was most frequent when addressing the distinction between marginal and wide margins. Considered the element of judgment inherent in all margin assessment, we find this reliability acceptable for using the Register for studies of local control of STS.
手术仍然是软组织肉瘤（STS）治疗的主要手段，在过去30年里一直是斯堪的纳维亚半岛大多数患者的主要治疗方法，尽管辅助放疗的使用有所增加。自1987年以来，患者和治疗特征已记录在斯堪的纳维亚肉瘤组（SSG）登记册中。在评估1998年新放疗指南的效果时，对不同斯堪的纳维亚机构之间手术切缘评估的可靠性进行了调查。一组肉瘤外科医生对切缘进行了重新评估，研究了从1998年至2003年期间接受治疗的470例记录患者中随机抽取的117例患者的病理和手术报告。在80%的病例中，该小组同意原始分类。在区分边缘切缘和广泛切缘时，分歧最为常见。考虑到所有切缘评估中固有的判断因素，我们发现使用该登记册进行STS局部控制研究时，这种可靠性是可以接受的。
