Brennan Ian M, Ahmed Muneeb
Ian M Brennan, Muneeb Ahmed, Section of Interventional Radiology, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA 02215, United States.
World J Radiol. 2012 May 28;4(5):224-7. doi: 10.4329/wjr.v4.i5.224.
Portal vein thrombosis is an uncommonly reported complication of percutaneous transhepatic cholangiography (PTC). A thorough review of the available literature shows no reported cases. In this case, a 29 year old female presented on two separate occasions with portal vein thrombosis following PTC without drain placement. This unusual complication of image guided percutaneous biliary access is unreported in the literature and prompted evaluation of the patient's coagulation parameters. A thrombophilia screen demonstrated a mutation in the Prothrombin (Factor II) gene. A thorough literature review shows no reported cases of portal vein thrombosis following percutaneous biliary access, is an unusual complication, and should raise suspicion of an underlying pro-coagulant state.
门静脉血栓形成是经皮肝穿刺胆管造影术（PTC）一种鲜有报道的并发症。对现有文献进行全面回顾后发现并无相关病例报道。在此病例中，一名29岁女性在两次独立的PTC术后且未放置引流管的情况下出现了门静脉血栓形成。影像引导下经皮胆道穿刺的这种罕见并发症在文献中尚无报道，这促使对该患者的凝血参数进行评估。血栓形成倾向筛查显示凝血酶原（因子II）基因突变。全面的文献回顾表明，经皮胆道穿刺后发生门静脉血栓形成尚无病例报道，这是一种罕见的并发症，应引起对潜在促凝状态的怀疑。
