I-123异丁基腈肟基苯甲胺单光子发射计算机断层显像中双侧顶叶异常的鉴别诊断

Differential diagnosis of bilateral parietal abnormalities in I-123 IMP SPECT imaging.

作者信息

Kuwabara Y, Ichiya Y, Otsuka M, Tahara T, Fukumura T, Gunasekera R, Masuda K

机构信息

Department of Radiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Clin Nucl Med. 1990 Dec;15(12):893-9. doi: 10.1097/00003072-199012000-00009.

DOI:10.1097/00003072-199012000-00009

PMID:2276232

Abstract

This report discusses the clinical significance of bilateral parietal abnormalities on I-123 IMP SPECT imaging in 158 patients with cerebral disorders. This pattern was seen in 15 out of 21 patients with Alzheimer's disease; it was also seen in 4 out of 5 patients with Parkinson's disease with dementia, in 3 out of 17 patients with vascular dementia, in 1 out of 36 patients with cerebral infarction without dementia, in 1 out of 2 patients with hypoglycemia, and in 1 out of 2 patients with CO intoxication. Detection of bilateral parietal abnormalities is a useful finding in the diagnosis of Alzheimer's disease, but one should keep in mind that other cerebral disorders may also show a similar pattern with I-123 IMP SPECT imaging.

摘要

本报告探讨了158例脑部疾病患者I-123异丁基异丙基胍单光子发射计算机断层扫描（SPECT）成像中双侧顶叶异常的临床意义。21例阿尔茨海默病患者中有15例出现这种模式；5例帕金森病伴痴呆患者中有4例出现这种模式，17例血管性痴呆患者中有3例出现这种模式，36例无痴呆的脑梗死患者中有1例出现这种模式，2例低血糖患者中有1例出现这种模式，2例一氧化碳中毒患者中有1例出现这种模式。双侧顶叶异常的检测在阿尔茨海默病的诊断中是一个有用的发现，但应记住，其他脑部疾病在I-123异丁基异丙基胍SPECT成像中也可能显示出类似的模式。