Department of Clinical and Theoretical Mental Health, Kútvölgyi Clinical Center, Semmelweis University, Kútvölgyi ut 4., 1125 Budapest, Hungary.
J Affect Disord. 2012 Dec 20;143(1-3):16-26. doi: 10.1016/j.jad.2012.04.041. Epub 2012 Jul 2.
Suicide is one of the leading causes of death and a major public health problem worldwide, and the majority of suicide attempters and completers suffer from some major affective disorder at the time of their death, which, in the majority of cases is unrecognized, under- or misdiagnosed and untreated.
Based on a systematic literature search, the authors give a detailed and critical overview of established risk factors of suicide in bipolar disorder.
Among affective disorders, bipolar disorder carries the highest risk of suicide, yet not all bipolar patients commit or even attempt suicide during their illness. While the general suicide risk factors also apply for bipolar disorders, there are several disease-specific risk factors as well which should be taken into account when evaluating suicide risk in case of patients.
It is crucial to identify suicide risk factors in bipolar disorder to be able to differentiate those patients within this already increased-risk illness group who are at especially high risk and therefore to allow for better prediction and prevention of suicidal acts.
自杀是全球主要的死亡原因和重大公共卫生问题之一，大多数自杀未遂者和自杀身亡者在死亡时都患有某种严重的情感障碍，但在大多数情况下，这些障碍未被识别、诊断不足或治疗不当。
基于系统文献检索，作者详细而批判性地概述了双相情感障碍中已确立的自杀风险因素。
在情感障碍中，双相情感障碍的自杀风险最高，但并非所有双相情感障碍患者在患病期间都会实施或甚至尝试自杀。虽然一般的自杀风险因素也适用于双相情感障碍，但也有一些特定于疾病的风险因素，在评估患者的自杀风险时应加以考虑。
在双相情感障碍中识别自杀风险因素至关重要，以便能够区分出那些在这个已经处于高风险的疾病群体中处于特别高风险的患者，从而能够更好地预测和预防自杀行为。
