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[骨水泥临时植入刮除术治疗骨巨细胞瘤]

[Curettage of giant cell tumors with temporary implantation of bone cement].

作者信息

Härle A, Wuisman P

机构信息

Orthop. Universitätsklinik, Münster.

出版信息

Z Orthop Ihre Grenzgeb. 1989 Jul-Aug;127(4):382-6. doi: 10.1055/s-2008-1044682.

DOI:10.1055/s-2008-1044682
PMID:2815936
Abstract

Curettage with simultaneous bone transplantation is followed by a recurrence rate of 20-60%. In a follow-up of own cases up to 36 years after treatment recurrence was roughly 50%. In the last 10 years we changed to on other treatment procedure, namely optical controlled curettage with temporary cementation. To prevent further damage to the preexisting destabilization of the periarticular cortical bone, tumor excision is done through a small bone window, using a cold lighted mirror to achieve complete curettage. The cavity is then filled with bone cement, which is left in place for 3 months. When at that time there are no signs for tumor persistence, the cement is removed and bone reconstruction performed. An analysis of 17 cases treated this way showed a clearly smaller recurrence rate of 6%; this difference was statistically significant when applying the Kaplan-Meier test.

摘要

刮除术联合同期骨移植后的复发率为20% - 60%。在对我们自己的病例进行长达36年的随访中,复发率约为50%。在过去10年里,我们改用了另一种治疗方法,即光学控制刮除术并临时植骨水泥。为防止进一步破坏关节周围皮质骨已有的稳定性,通过一个小骨窗进行肿瘤切除,使用冷光镜以实现彻底刮除。然后用骨水泥填充骨腔,并留置3个月。如果届时没有肿瘤持续存在的迹象,则取出骨水泥并进行骨重建。对17例采用这种方法治疗的病例进行分析显示,复发率明显降低至6%;应用Kaplan - Meier检验时,这种差异具有统计学意义。

相似文献

1
[Curettage of giant cell tumors with temporary implantation of bone cement].[骨水泥临时植入刮除术治疗骨巨细胞瘤]
Z Orthop Ihre Grenzgeb. 1989 Jul-Aug;127(4):382-6. doi: 10.1055/s-2008-1044682.
2
Does the addition of cement improve the rate of local recurrence after curettage of giant cell tumours in bone?在骨巨细胞瘤刮除术后添加骨水泥是否能提高局部复发率?
J Bone Joint Surg Br. 2011 Dec;93(12):1665-9. doi: 10.1302/0301-620X.93B12.27663.
3
[Surgical treatment of giant cell tumor of bone--a report of 50 cases].[骨巨细胞瘤的外科治疗——附50例报告]
Zhonghua Zhong Liu Za Zhi. 1990 Sep;12(5):389-91.
4
[Diagnosis of recurrence and therapy of recurrence with in situ bone cement filling in the treatment of giant cell tumor].[骨巨细胞瘤治疗中复发的诊断及原位骨水泥填充治疗复发]
Z Orthop Ihre Grenzgeb. 1989 Jul-Aug;127(4):379-81. doi: 10.1055/s-2008-1044681.
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[Results following spongiosa transplantation in giant cell tumor of bone].
Z Orthop Ihre Grenzgeb. 1989 Jul-Aug;127(4):387-91. doi: 10.1055/s-2008-1044683.
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[Use of acrylic cement after curettage in the treatment of giant cell tumors].
Chir Organi Mov. 1987 Jan-Mar;72(1):1-6.
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Long bones giant cells tumors: treatment by curretage and cavity filling cementation.长骨巨细胞瘤:刮除与空腔填充骨水泥填充治疗。
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[The role of a bone cement filling in intralesional tumor treatment].[骨水泥填充在瘤内肿瘤治疗中的作用]
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Curettage and acrylic cementation in surgery of giant cell tumors of bone.
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引用本文的文献

1
Giant cell tumor of bone: treatment and outcome of 214 cases.骨巨细胞瘤:214例患者的治疗与预后
J Cancer Res Clin Oncol. 2008 Sep;134(9):969-78. doi: 10.1007/s00432-008-0370-x. Epub 2008 Mar 6.