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[伴有环状小管的卵巢性索肿瘤——附7例报告]

[Ovarian sex cord tumor with annular tubules--a report of 7 cases].

作者信息

Li X Z

机构信息

81 Hospital, PLA, Nanjing.

出版信息

Zhonghua Zhong Liu Za Zhi. 1990 Sep;12(5):392-4.

PMID:2276337
Abstract

Seven cases of ovarian sex cord tumor with annular tubules are reported in this paper. All lesions occurred in the young (6-25 years of age with a mean of 15 years) without Poutz-Jeghers syndrome. Four cases had estrogenic hormonal imbalance and abdominal mass. Gross examination revealed that the tumors were unilateral with smooth surface. Except one, all showed varying degrees of cystic degeneration on section. The sections appeared as roe-like granular substance in a pale yellowish brown shade in the parenchymal region. Microscopic examination showed single or complex annular tubules with prominent basement membrane-like material around the tubules. Lipid in the cytoplasm and granulosa cell tumor-like differentiation were observed in isolated area of some cases. Ultrastructurally, Charcot-Battcher filaments were found in 1 case, indicating differentiation towards Sertoli's cells. The malignant potential of this tumor had been elucidated in the literature.

摘要

本文报道了7例环形小管性卵巢性索肿瘤。所有病变均发生于年轻人(年龄6 - 25岁,平均15岁),无波伊茨-耶格综合征。4例有雌激素失衡和腹部肿块。大体检查显示肿瘤为单侧,表面光滑。除1例之外,所有病例在切片上均显示不同程度的囊性变。切片在实质区域呈现为淡黄褐色的鱼子样颗粒物质。显微镜检查显示单个或复杂的环形小管,小管周围有明显的类似基底膜的物质。部分病例的孤立区域可见细胞质内脂质及颗粒细胞瘤样分化。超微结构检查在1例中发现了夏科-贝切细丝,提示向支持细胞分化。该肿瘤的恶性潜能已在文献中阐明。

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