Mölstad S, Hovelius B, Kroon L, Melander A
Community Health Centre, Höör, Sweden.
Eur J Clin Pharmacol. 1990;39(1):9-12. doi: 10.1007/BF02657048.
Prescription of antibiotics in Sweden varies between countries within a range of 13-20 DDD/1000 inhabitants/day. In Malmöhus county, which accounts for the highest prescription rate, the amounts and proportions of erythromycin and tetracyclin prescribed are particularly large. All prescriptions for antibiotics dispensed in half of the pharmacies in the county during a one-week period were examined with respect to type of antibiotic and category of physician responsible for the prescription. Among 5,165 antibiotic prescriptions examined, broad spectrum antibiotics were more frequent in urban than in rural areas, and were more often prescribed by hospital physicians and private practitioners than by district physicians. Erythromycin was particularly often prescribed by paediatricians, the frequency being comparable to that of phenoxymethylpenicillin. Retrospective analysis of consultations at the ENT and paediatric clinics for respiratory tract infections showed that phenoxymethylpenicillin was not always the drug of choice by hospital physicians, despite a recommendation to that effect by the Board of Health and Welfare. The findings suggest that the choice of antibiotics is determined not only by medically relevant factors and Board recommendations but also by the habits of the consulting physicians.
瑞典抗生素的处方量在不同地区有所差异,范围为每1000居民每天13 - 20限定日剂量(DDD)。在处方率最高的马尔默胡斯郡,红霉素和四环素的处方量及所占比例尤为大。对该郡一半药店在一周内配发的所有抗生素处方,就抗生素类型和开处方医生类别进行了检查。在检查的5165份抗生素处方中,广谱抗生素在城市比在农村更常见,且医院医生和私人执业医生比地区医生开得更频繁。红霉素尤其常由儿科医生开处方,其频率与苯氧甲基青霉素相当。对耳鼻喉科和儿科诊所呼吸道感染会诊的回顾性分析表明,尽管卫生与福利委员会有相关推荐,但苯氧甲基青霉素并非总是医院医生的首选药物。研究结果表明,抗生素的选择不仅取决于医学相关因素和委员会的建议,还取决于会诊医生的习惯。