Mansoor Muhammad Sohail, Khan Muhammad Bilal Salman
Medical Ward-D, Khyber Teaching Hospital, Peshawar.
J Pak Med Assoc. 2012 Mar;62(3):289-90.
A 22 years old patient presented with recurrent episodes of diarrhoea, pharyngitis, apthous ulcers and fever for the past 6 months. The episodes lasted a week each time. The patient was admitted and blood studies revealed neutropenia with increased number of Large Granular Lymphocytes. Later on it was found out that his neutrophil count dropped to less than 0.2 x 10(9)/L after every 3 weeks. Bone marrow study revealed decreases neutrophil precursors during these episodes. He was diagnosed with adult onset cyclic neutropenia and his episodes were treated with G-CSF and Ceftriaxone.
一名22岁患者在过去6个月中反复出现腹泻、咽炎、口腔溃疡和发热症状。每次发作持续一周。患者入院,血液检查显示中性粒细胞减少,大颗粒淋巴细胞数量增加。后来发现他的中性粒细胞计数每3周就会降至低于0.2×10⁹/L。骨髓检查显示在这些发作期间中性粒细胞前体细胞减少。他被诊断为成人期周期性中性粒细胞减少症,其发作通过使用粒细胞集落刺激因子(G-CSF)和头孢曲松进行治疗。