Lahlimi Fatima Ezzahra, Khalil Khawla, Lahiaouni Soumia, Tazi Illias
Hematology Department, University Hospital Mohamed VI, Faculty of Medicine, Cadi Ayyad University, Marrakech, Morocco.
Case Rep Pediatr. 2020 Dec 1;2020:8858764. doi: 10.1155/2020/8858764. eCollection 2020.
Neutropenic enterocolitis is a syndrome characterized by fever and abdominal pain in a neutropenic patient. It is often reported in children treated for leukemia and rarely reported in patients with other diseases. Herein, we report the case of a 9-year-old patient with a medical history of recurrent fever and mouth ulcers since the age of 4, who presented with neutropenic enterocolitis complicated with intestinal perforation which all leaded to disclose cyclic neutropenia. The patient was successfully treated by aggressive supportive care combined with surgical intervention. Neutropenic enterocolitis with possible complications should be considered and promptly managed in every neutropenic patient and may reveal a rare cause of neutropenia as cyclic neutropenia.
中性粒细胞减少性小肠结肠炎是一种以中性粒细胞减少患者发热和腹痛为特征的综合征。它常在接受白血病治疗的儿童中报道，而在其他疾病患者中很少见。在此，我们报告一例9岁患者，自4岁起有反复发热和口腔溃疡病史，该患者出现中性粒细胞减少性小肠结肠炎并伴有肠穿孔，所有这些均导致发现周期性中性粒细胞减少症。该患者通过积极的支持治疗联合手术干预获得成功治疗。对于每一位中性粒细胞减少患者，均应考虑并及时处理可能伴有并发症的中性粒细胞减少性小肠结肠炎，其可能揭示一种罕见的中性粒细胞减少病因，即周期性中性粒细胞减少症。
